Digital quantification of the MMSE interlocking pentagon areas: a three-stage algorithm.
Digital quantification of the MMSE interlocking pentagon areas: a three-stage algorithm.
复制标题
MMSE 联锁五边形区域的数字量化：三阶段算法。
DOI：
10.1038/s41598-024-59194-1
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发表时间：
2024
影响因子：
4.6
通讯作者：
Tasaki,Shinya
中科院分区：
文献类型：
--
作者：
Kim,Namhee;Truty,Timothy;DukeHan,S;Heo,Moonseong;Buchman,AronS;Bennett,DavidA;Tasaki,Shinya
简易精神状态检查（MMSE）是一种广泛使用的认知障碍严重程度筛查工具。在 MMSE 项目中，五边形复制测试（PCT）要求参与者准确复制两个互锁五边形的样本。虽然 PCT 传统上采用二进制评分，但用于评估任务绩效的细粒度评分尺度的发展有限。在本文中，我们提出了一种新颖的三阶段算法，称为联锁五边形量化（QIP），该算法通过计算各个五边形的面积及其相交面积以及两个单独五边形面积之间的平衡比来量化 PCT 性能。 QIP 算法的三个阶段包括：(1) 检测线段，(2) 解开互锁的五边形，以及 (3) 面积量化。来自 84 名参与者的一组 497 个 PCT，包括来自 Rush Memory and Aging Project 的基线和后续 PCT，是在不了解他们的认知和临床状态的情况下选择的。对量化数据的分析显示，年龄与平衡比之间存在显着的负相关关系（beta = − 0.49，p= 0.0033），表明年龄较大与较小的平衡比相关。此外，平衡比与知觉速度（r = 0.71，p= 0.0135）、血管危险因素（beta = − 3.96，p= 0.0269）和医疗状况（beta = − 2.78，p= 0.0389）相关。 QIP 算法可以作为提高 PCT 表现评分的有用工具。
The Mini-Mental State Examination (MMSE) is a widely employed screening tool for the severity of cognitive impairment. Among the MMSE items, the pentagon copying test (PCT) requires participants to accurately replicate a sample of two interlocking pentagons. While the PCT is traditionally scored on a binary scale, there have been limited developments of granular scoring scale to assess task performance. In this paper, we present a novel three-stage algorithm, called Quantification of Interlocking Pentagons (QIP) which quantifies PCT performance by computing the areas of individual pentagons and their intersection areas, and a balance ratio between the areas of the two individual pentagons. The three stages of the QIP algorithm include: (1) detection of line segments, (2) unraveling of the interlocking pentagons, and (3) quantification of areas. A set of 497 PCTs from 84 participants including their baseline and follow-up PCTs from the Rush Memory and Aging Project was selected blinded about their cognitive and clinical status. Analysis of the quantified data revealed a significant inverse relationship between age and balance ratio (beta = − 0.49,p= 0.0033), indicating that older age was associated with a smaller balance ratio. In addition, balance ratio was associated with perceptual speed (r = 0.71,p= 0.0135), vascular risk factors (beta = − 3.96,p= 0.0269), and medical conditions (beta = − 2.78,p= 0.0389). The QIP algorithm can serve as a useful tool for enhancing the scoring of performance in the PCT.