Residential greenness and prevalence of major depressive disorders: a cross-sectional, observational, associational study of 94 879 adult UK Biobank participants
Residential greenness and prevalence of major depressive disorders: a cross-sectional, observational, associational study of 94 879 adult UK Biobank participants
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DOI：
10.1016/s2542-5196(18)30051-2
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发表时间：
2018-04-01
影响因子：
25.7
通讯作者：
Gallacher, John
中科院分区：
文献类型：
--
作者：
Sarkar, Chinmoy;Webster, Chris;Gallacher, John
城市化程度的提高以及个人与自然环境接触的减少导致了包括抑郁症在内的精神障碍的增加。住宅绿化是城市设计的基本组成部分，已被证明可以减轻精神障碍的公共卫生负担。本研究使用来自英国生物银行的大型和多样化的横断面数据集调查了住宅绿色暴露与重度抑郁症患病率之间的关系。在这项横断面、观察性、相关性研究中，我们使用了来自英国生物银行37-73岁参与者队列的基线数据。环境暴露数据来源于建模和链接的建筑环境数据库。住宅绿化率通过0.5 m分辨率的归一化植被指数进行评估，该指数来源于遥感彩色红外数据的光谱反射率测量，并在地理编码的住宅集水区内进行测量。其他环境指标包括街道水平的运动密度、地形和细颗粒物暴露。在调整活动影响环境和个体协变量后，一系列逻辑模型检验了住宅绿化与重度抑郁症几率之间的关系。研究结果：在2009年4月29日至2010年10月1日期间，从10个英国生物银行评估中心招募了122993名有重度抑郁症数据的参与者，分析样本包括94879名（77.1%）参与者。绿色对抑郁症的保护作用被一致观察到，标准化植被指数绿色每增加四分位数，重度抑郁症的几率降低4.0%（优势比0.960,95% CI 0.93-0.99; p=0.0044）。相互作用分析表明，绿化的有益影响在女性、60岁以下的参与者以及居住在低社区社会经济地位或高城市化地区的参与者中更为明显。研究结果表明，精心设计的绿色环境对心理健康有益。需要进一步的纵向研究来解读因果关系。在英国，旨在优化绿色空间分配和设计的政策可能有助于保护心理生态系统服务，从而改善人口的心理健康，增强城市的心理资本。版权所有(C) 2018作者。Elsevier Ltd.出版。
Background Increased urbanisation and the associated reduced contact of individuals with natural environments have led to a rise in mental disorders, including depression. Residential greenness, a fundamental component of urban design, has been shown to reduce the public health burden of mental disorders. The present study investigates the association between residential green exposure and prevalence of major depressive disorders using a large and diverse cross-sectional dataset from the UK Biobank.Methods In this cross-sectional, observational, associational study, we used baseline data from the UK Biobank cohort of participants aged 37-73 years from across the UK. Environmental exposure data were derived from a modelled and linked built environment database. Residential greenness was assessed with a 0.5 m resolution Normalised Difference Vegetation Index, which is derived from spectral reflectance measurements in remotely sensed colour infrared data and measured within geocoded dwelling catchments. Other environment metrics included street-level movement density, terrain, and fine particulate exposures. A series of logistic models examined associations between residential greenness and odds of major depressive disorder after adjusting for activity-influencing environments and individual covariates.Findings Of 122 993 participants with data on major depressive disorder, the study analytical sample comprised 94 879 (77.1%) participants recruited across ten UK Biobank assessment centres between April 29, 2009, and Oct 1, 2010. A protective effect of greenness on depression was consistently observed, with 4.0% lower odds of major depressive disorder per interquartile increment in Normalised Difference Vegetation Index greenness (odds ratio 0.960, 95% CI 0.93-0.99; p=0.0044). Interaction analyses indicated that the beneficial effects of greenness were more pronounced among women, participants younger than 60 years, and participants residing in areas with low neighbourhood socioeconomic status or high urbanicity.Interpretation The results point to the benefits of well designed green environments on mental health. Further longitudinal studies are needed to decipher causal pathways. In the UK, policies aimed at optimising allocation and design of green spaces might help preserve psychological ecosystem services, thereby, improving the mental wellbeing of populations and enhancing the mental capital of cities. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd.