The role of the sympathetic nervous system in moxibustion-induced immunomodulation in rats
The role of the sympathetic nervous system in moxibustion-induced immunomodulation in rats
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DOI：
10.1016/s0165-5728(03)00211-x
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发表时间：
2003-07-01
影响因子：
3.3
通讯作者：
Min, BI
中科院分区：
文献类型：
--
作者：
Han, JB;Oh, SD;Min, BI
研究了化学交感神经切断对艾灸引起的脾NK细胞杀伤活性、T细胞和B细胞增殖的影响。直接艾灸治疗单侧足三里穴。艾灸对赋形剂治疗大鼠和交感神经切除大鼠的NK细胞杀伤活性均有抑制作用。艾灸对T细胞增殖无明显影响。赋形剂治疗组大鼠B细胞增殖无明显变化，而艾灸治疗组大鼠交感神经切断后B细胞增殖明显增加。单独切除交感神经可增强NK细胞的细胞毒作用，抑制T细胞的增殖。提示交感神经系统在艾灸免疫调节机制中无明显作用。(C)2003爱思唯尔B.V.保留所有权利。
The effects of chemical sympathectomy on moxibustion-induced changes in splenic natural killer (NK) cell cytotoxicity, T and B cell proliferation were studied. Direct moxibustion was applied to the unilateral Zusanli region. NK cell cytotoxicity was suppressed by moxibustion in both vehicle-treated rats and sympathectomized rats. T cell proliferation was not affected by moxibustion. B cell proliferation showed no significant change in vehicle-treated rats, but an increase was seen in sympathectomized rats treated with moxibustion. Sympathectomy alone induced an augmentation of NK cell cytotoxicity and a suppression of T cell proliferation. These results suggest that the sympathetic nervous system (SNS) has no significant role in the mechanism of moxibustion-induced immunomodulation. (C) 2003 Elsevier B.V. All rights reserved.