Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats

Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats
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天麻素可减轻 DOI 诱导的大鼠抽动秽语综合征中的神经炎症

DOI:
10.1002/jbt.22302
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发表时间:
2019-05-01
影响因子:
3.6
通讯作者:
Huang, Yaruo
Huang, Yaruo
中科院分区:
医学4区
文献类型:
--
作者:
Long, Hongyan;Wang, Chunyan;Huang, Yaruo

文献摘要

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抽动秽语综合征(TS)是一种慢性神经精神疾病。其临床表现为不自主的、反复发作的肌肉抽搐,导致运动性抽搐和发生性抽搐。中医药治疗TS具有明显优势。研究天麻素对1-(2,5-二甲氧基-4-碘苯基)-2-氨基丙烷(DOI)诱导的大鼠TS的影响及其机制。
Tourette syndrome (TS) is a chronic neuropsychiatric disorder. Its clinical manifestations are involuntary and recurrent muscle twitch, resulting in motor twitch and occurrence twitch. Traditional Chinese medicine has obvious advantages in treating TS. The aim of this study was to investigate the effects and mechanism of gastrodin on 1‐(2,5‐dimethoxy‐4‐iodophenyl)‐2‐aminopropane (DOI)‐induced TS in rats.