Electrochemical non-enzymatic glucose sensors based on nano-composite of Co3O4 and multiwalled carbon nanotube
Electrochemical non-enzymatic glucose sensors based on nano-composite of Co3O4 and multiwalled carbon nanotube
复制标题
基于Co_3O_4和多壁碳纳米管纳米复合材料的电化学非酶葡萄糖传感器
DOI：
10.1016/j.cclet.2019.04.009
复制
发表时间：
2019-06-01
影响因子：
9.1
通讯作者：
Ni, Yongnian
中科院分区：
文献类型：
--
作者：
Lin, Xiaoyun;Wang, Yanfang;Ni, Yongnian
采用一步溶剂热法合成了Co3O4与多壁碳纳米管（MCNT）的纳米复合材料，并通过滴法成功构建了电化学无酶葡萄糖传感器（Co3O4-MCNT/GCE）。用透射电子显微镜（TEM）和能谱仪（EDS）对所得的Co3O4和Co3O4- MCNT进行了表征和研究。葡萄糖的定量分析采用电流法（i-t），电流差与葡萄糖浓度在1.0 ~ 122 μ mol/L范围内呈线性关系，线性相关系数（R-2）为0.9983，检出限（LOD）为0.28 μ mol/L。该传感器的灵敏度评估为2550 μ A L mmol(-1) cm（-2）。该传感器具有良好的重现性和稳定性，可用于人血清样品中微量葡萄糖的监测。(C) 2019中国化学学会，中国医学科学院药物研究所。Elsevier B.V.版权所有。
Nanocomposite of Co3O4 and multiwalled carbon nanotube (MCNT) was synthesised using one step solvothermal method, and an electrochemical non-enzymatic glucose sensor (Co3O4-MCNT/GCE) was successfully constructed by a dropping method. The obtained Co3O4 and Co3O4- MCNT were characterized and investigated by transmission electron microscopy (TEM) and energy dispersive Xray spectroscopy (EDS). Quantitative analysis of glucose was performed using the amperometric (i-t) method, and plot of current difference versus concentration of glucose was linear in the range of 1.0-122 mu mol/L, with a linear correlation coefficient (R-2) of 0.9983 and limit of detection (LOD) of 0.28 mu mol/L. Sensitivity of this sensor was evaluated as 2550 mu A L mmol(-1) cm(-2). This new sensor produced satisfactory reproducibility and stability and was applied to monitor trace amounts of glucose in human serum samples. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.