SEASONAL RECRUITMENT OF HIPPOCAMPAL-NEURONS IN ADULT FREE-RANGING BLACK-CAPPED CHICKADEES
SEASONAL RECRUITMENT OF HIPPOCAMPAL-NEURONS IN ADULT FREE-RANGING BLACK-CAPPED CHICKADEES
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DOI：
10.1073/pnas.91.23.11217
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发表时间：
1994-11-08
影响因子：
11.1
通讯作者：
NOTTEBOHM, F
中科院分区：
文献类型：
--
作者：
BARNEA, A;NOTTEBOHM, F
描述了野生自由放养动物群体中的神经发生和神经元替代。我们的研究对象是成年黑顶山雀（Parus atricapillus）。神经元的出生日期，确定了一个单一的全身注射[H-3]胸苷，然后释放的鸟和其夺回6周或更长时间后。新形成的神经元出现在海马复合体在一年中的所有时间，但在秋季（10月）有一个显着的高峰。新的神经元也被添加到圈养山雀的海马复合体中，但水平只有野生鸟类的一半。在一年的不同时间出生的神经元生活了几个月，然后消失了，我们认为，神经元添加的神经元是神经元替换过程的一部分，它们对于获得新的空间记忆很重要，这一需求在秋季尤为迫切。激素和经验因素可能决定神经元的替代率。
Neurogenesis and neuronal replacement in a population of wild free-ranging animals are described. Our subjects were adult black-capped chickadees (Parus atricapillus). Neuronal birth dates were determined by a single systemic injection of [H-3]thymidine, followed by release of the bird and its recapture 6 or more weeks later. Newly formed neurons appeared in the hippocampal complex during all times of year, but with a marked peak in the fall (October). New neurons were also added to the hippocampal complex of captive chickadees, but at levels only half as high as seen in the wild birds. Neurons born at different times of the year lived for a few months and then disappeared, We suggest that the neurons added are part of a process of neuronal replacement and that they are important for the acquisition of new spatial memories, a need that is particularly acute in the fall. Hormonal and experiential factors may determine the rate of neuronal replacement.