A POSITIVE ASSOCIATION BETWEEN MATERNAL SERUM ZINC CONCENTRATION AND BIRTH-WEIGHT
A POSITIVE ASSOCIATION BETWEEN MATERNAL SERUM ZINC CONCENTRATION AND BIRTH-WEIGHT
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DOI：
10.1093/ajcn/51.4.678
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发表时间：
1990-04-01
影响因子：
7.1
通讯作者：
ROSEMAN, JM
中科院分区：
文献类型：
--
作者：
NEGGERS, YH;CUTTER, GR;ROSEMAN, JM
对476名妇女（364名黑人，112名白色）进行了一项研究，这些妇女参加了杰斐逊县卫生局诊所的产前护理，以确定妊娠早期测量的母体血清锌浓度与出生体重之间的关系。对于所有的主题，母亲血清锌显着相关的出生体重后，各种独立的决定因素的出生体重控制。在这项研究中的数据表明，母亲血清锌浓度的阈值低于低出生体重的患病率显着增加。血清锌浓度在最低四分位数的孕妇有显着较高的患病率低出生体重比那些母亲在怀孕期间血清锌浓度在上三个四分位数。这些研究结果表明，孕妇血清锌浓度测量在怀孕早期可以用来确定那些妇女在较高的风险，生下一个低出生体重儿。
A study was conducted on a cohort of 476 women (364 black, 112 white), who attended the Jefferson County Health Department clinic for their prenatal care, to ascertain the relationship between maternal serum zinc concentration measured early in pregnancy and birth weight. For all subjects maternal serum zinc was significantly related to birth weight after various independent determinants of birth weight were controlled for. The data in this study indicate a threshold for maternal serum zinc concentration below which the prevalence of low birth weight increases significantly. Pregnant women who had serum zinc concentrations in the lowest quartile had significantly higher prevalence of low birth weight than did those mothers who had serum zinc concentrations in the upper three quartiles during pregnancy. These findings suggest that maternal serum zinc concentration measured early in pregnancy could be used to identify those women at higher risk of giving birth to a low-birth-weight infant.