Social modulation of stress responses
Social modulation of stress responses
复制标题
DOI：
10.1016/s0031-9384(03)00152-5
复制
发表时间：
2003-08-01
影响因子：
2.9
通讯作者：
Detillion, CE
中科院分区：
文献类型：
--
作者：
DeVries, AC;Glasper, ER;Detillion, CE
社会互动可以深刻地影响下丘脑-垂体-肾上腺（HPA）轴。虽然大多数关于糖皮质激素浓度的社会调节的研究都集中在暴露于压力性社会刺激的后果上，但越来越多的文献表明，人类的社会支持和某些动物的亲和行为可以提供对压力的缓冲，并对健康和福祉的措施产生积极影响。本综述将比较HPA轴活动的个人之间的社会关系是通过积极的显示，如统治阶层，与个人从事高水平的亲社会行为。我们还将研究催产素，一种以促进社会行为而闻名的神经肽，作为积极的社会互动和HPA轴抑制之间的生理联系。尽管有许多社会互动调节HPA轴和改善健康结果的例子，但关于社会行为可以为压力相关疾病提供缓冲的潜在机制，人们知之甚少。(C)2003年爱思唯尔公司All rights reserved.
Social interactions can profoundly affect the hypothalamic-pituitary-adrenal (HPA) axis. Although most research on social modulation of glucocorticoid concentrations has focused on the consequences of exposure to stressful social stimuli, there is a growing body of literature which suggests that social support in humans and affiliative behaviors in some animals can provide a buffer against stress and have a positive impact on measures of health and well-being. This review will compare HPA axis activity among individuals for whom social relationships are maintained through aggressive displays, such as dominance hierarchies, vs. individuals engaging in high levels of prosocial behavior. We also will examine oxytocin, a neuropeptide that is well known for promoting social behavior, as the physiological link between positive social interactions and suppression of the HPA axis. Despite many examples of social interaction modulating the HPA axis and improving health outcomes, there is relatively little known regarding the underlying mechanisms through which social behavior can provide a buffer against stress-related disease. (C) 2003 Elsevier Inc. All rights reserved.