Risk mapping and early warning systems for the control of meningitis in Africa
Risk mapping and early warning systems for the control of meningitis in Africa
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DOI：
10.1016/j.vaccine.2007.04.034
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发表时间：
2007-09-03
期刊：
影响因子：
5.5
通讯作者：
Thomson, Madeleine C.
中科院分区：
文献类型：
--
作者：
Cuevas, Luis E.;Jeanne, Isabelle;Thomson, Madeleine C.
脑膜炎球菌性脑膜炎在非洲的流行病已经困扰该大陆超过一个世纪。这些流行病与环境密切相关，目前正在努力开发预测其发生地点和发病率的模型。本综述介绍了基于目前可用的气候/环境信息的预测模型，介绍了正在进行的工作，并提供了证据表明，流行病的分布正在以与环境变化相适应的模式发生变化。还讨论了非洲新结合疫苗研究的优先事项。(C)2007爱思唯尔有限公司保留所有权利。
Epidemics of meningococcal meningitis in Africa have plagued the continent for over a century. These epidemics have a strong association with the environment and efforts are being made to develop models to predict both their location and their incidence. This review describes the predictive models based on climate/environmental information currently available, describes work in progress, and presents evidence that the distribution of the epidemics is changing in a pattern that is compatible with changes in the environment. Discussion of priorities for research in the context of the new conjugate vaccines in Africa is also provided. (C) 2007 Elsevier Ltd. All rights reserved.