Statistical analysis of honeybee survival after chronic exposure to insecticides
Statistical analysis of honeybee survival after chronic exposure to insecticides
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DOI：
10.1897/02-578
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发表时间：
2003-12-01
影响因子：
4.1
通讯作者：
Pham-Delègue, MH
中科院分区：
文献类型：
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作者：
Moncharmont, FXD;DeCourtye, A;Pham-Delègue, MH
有关蜜蜂长期生存的研究提出了死亡率数据统计分析的问题。在本研究中，我们使用了长期暴露于两种农药（吡虫啉和溴氰菊酯）的笼养蜜蜂生存数据的建模方法。我们的模型基于 Cox 比例风险模型，不限于特定的风险函数形式（例如参数方法），而是考虑多个协变量。我们不仅考虑农药处理，还考虑一个令人讨厌的变量（重复之间的变异性）。此外，考虑到社会互动的发生，该模型整合了蜜蜂不会独立死亡的事实。我们证明了吡虫啉和溴氰菊酯引起的慢性毒性。我们的结果还强调了重复效应、密度依赖性效应的作用以及它们与治疗效果的相互作用。在评估农药对蜜蜂的慢性毒性时，这些参数都不能忽视。
Studies concerning long-term Survival of honeybees raise the problem of the statistical analysis of mortality data. In the present study, we used a modeling approach of survival data of caged bees under chronic exposure to two pesticides (imidacloprid and deltamethrin). Our model, based on a Cox proportional hazard model, is not restricted to a specific hazard functional form, such as in parametric approaches, but takes into account multiple covariates. We consider not only the pesticide treatment but also a nuisance variable (variability between replicates). Moreover, considering the occurrence of social interactions, the model integrates the fact that bees do not die independently of each other. We demonstrate the chronic toxicity induced by imidacloprid and deltamethrin. Our results also underline the role of the replicate effect, the density-dependent effect, and their interactions with the treatment effect. None of these parameters can be neglected in the assessment of chronic toxicity of pesticides to the honeybee.