Serous detachment of the ciliary body in Harada disease.
Serous detachment of the ciliary body in Harada disease.
复制标题
原田病中睫状体浆液性脱离。
DOI：
10.1016/s0002-9394(98)00033-6
复制
发表时间：
1998
影响因子：
4.2
通讯作者：
K. Shimizu
中科院分区：
文献类型：
--
作者：
Y. Maruyama;Y. Kimura;S. Kishi;K. Shimizu
目的探讨原田病是否累及眼前节。方法采用前瞻性研究方法，对9例(18眼)原田病急性期患者在全身应用糖皮质激素治疗前后进行超声生物显微镜检查。每隔3天复查一次，直至浆液性视网膜脱离消失。结果治疗前18只眼中有11只眼(61%)有浆液性睫状体脱离。11只眼中有10只眼睫状体周围脱离。睫状体脱离高度为巩膜厚度的20%~250%。视网膜脱离范围越大，睫状体脱离越明显。睫状体脱离的发生率与虹膜炎症的严重程度无关。治疗第3天，7只眼睫状体脱离消失。另4只眼高度缩小至巩膜厚度的10%以下。视网膜脱离在治疗的第6天到第17天(平均第11天)消失。1例患者双眼前房非常浅。这些眼在巩膜厚度的250%处表现出高度的睫状体脱离。另1例双眼出现−5.0D的一过性近视。结论睫状体脱离是原田病急性期的常见表现。治疗后较浆液性视网膜脱离消退快。睫状体脱离可能与浅前房的形成有关。
PurposeTo evaluate the involvement of the anterior ocular segment in Harada disease.MethodsIn a prospective study, ultrasound biomicroscopy was performed in 18 consecutive eyes of nine patients with Harada disease in its acute phase before and after onset of systemic corticosteroid therapy. Examination was repeated every 3 days until the resolution of serous retinal detachment.ResultsSerous detachment of the ciliary body was present in 11 (61%) of 18 eyes before treatment. The circumference of the ciliary body was detached in 10 of the 11 eyes. The height of ciliary detachment ranged from 20% to 250% of the scleral thickness. Ciliary detachment was more prominent in eyes with more extensive retinal detachment. There was no relation between the frequency of ciliary detachment and the severity of iritis. On day 3 of treatment, ciliary detachment had disappeared in seven eyes. In the other four eyes, it diminished in height to less than 10% of scleral thickness. Retinal detachment disappeared on days 6 through 17 (mean, day 11) of treatment. Two eyes of one patient showed very shallow anterior chambers. These eyes showed high ciliary detachment at 250% of scleral thickness. In another patient, both eyes developed −5.0 diopters of transient myopia.ConclusionCiliary detachment was a frequent finding in the acute stage of Harada disease. Its resolution was more prompt than that of serous retinal detachment after treatment. Ciliary detachment may be related to the development of a shallow anterior chamber.