Quantitative end-tidal CO2 can predict increase in heart rate during infant cardiopulmonary resuscitation
Quantitative end-tidal CO2 can predict increase in heart rate during infant cardiopulmonary resuscitation
复制标题
DOI：
10.1016/j.heliyon.2019.e01871
复制
发表时间：
2019-06-01
期刊：
影响因子：
4
通讯作者：
Wyckoff, Myra H.
中科院分区：
文献类型：
--
作者：
Stine, Christina N.;Koch, Josh;Wyckoff, Myra H.
目的：确定在CVICU/PICU新生儿/婴儿心肺复苏（CPR）（胸外按压+/-肾上腺素）期间预测HR bb0 / 60次/分钟（bpm）的潮末CO2 （ETCO2）值的最佳敏感性和特异性。方法：这是一项回顾性队列研究，从2008年1月1日至2012年12月31日，所有婴儿60 bpm。ROC曲线下面积为0.835。结论：本研究提供了新生儿和婴幼儿心肺复苏术中ETCO2值与心率适当升高之间相关性的关键临床信息。定量ETCO2监测允许心肺复苏术不间断地进行，而不需要每60秒暂停一次检查心率，直到达到关键的ETCO2阈值。定量ETCO2监测作为婴儿心肺复苏术中心脏监测的辅助可能会增强灌注并改善预后。
Aim: To determine the end-tidal CO2 (ETCO2) value that predicts a HR > 60 beats per minute (bpm) with the best sensitivity and specificity during neonatal/infant cardiopulmonary resuscitation (CPR) defined as chest compressions +/- epinephrine in neonates/infants admitted to a CVICU/PICU.Methods: This was a retrospective cohort study from 1/1/08 to 12/31/12 of all infants 60 bpm. Area under the curve for the ROC is 0.835.Conclusions: This study provides critical clinical information regarding correlation between ETCO2 values and an adequate rise in heart rate in neonates and young infants during CPR. Quantitative ETCO2 monitoring allows CPR to progress uninterrupted without need to pause to check heart rate every 60 seconds until the critical ETCO2 threshold is reached. Quantitative ETCO2 monitoring as an adjunct to cardiac monitoring during infant CPR might enhance perfusion and improve outcomes.