Physical therapy and Parkinson's disease
Physical therapy and Parkinson's disease
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物理治疗和帕金森病
作者：
C. L. Comelia;G. Stebbins;Nancy Brown;C. Goetz
在一项随机、单盲、交叉研究中，我们评估了中晚期帕金森病（PD）患者在4周正常体力活动和4周强化身体康复计划后的身体残疾。我们使用了定时运动任务和PD严重程度的标准评估（统一帕金森病评定量表（Unified Parkinson's Disease Rating Scale，简称PDRS），包括精神状态、日常生活活动（Activities of Daily Living，简称ADL）和运动功能的子量表），由一名对患者的身体康复状况不知情的研究者完成。康复治疗后，患者的ADL和运动评分有显著改善，但精神状态评分无变化。在物理康复后的6个月内，患者没有定期锻炼，并且BPRS评分恢复到基线水平。我们的结论是，身体残疾的中晚期PD客观上改善了定期的身体康复计划，但这种改善是不持续的正常活动恢复。
In a randomized, single-blind, crossover study, we evaluated physical disability in moderately advanced Parkinson's disease (PD) patients after 4 weeks of normal physical activity and 4 weeks of an intensive physical rehabilitation program. We used a timed motor task and a standard assessment of PD severity (the Unified Parkinson's Disease Rating Scale [UPDRS] with subscales for mentation, activities of daily living [ADL], and motor function) completed by an investigator blinded to the physical rehabilitation status of the patient. Following physical rehabilitation, there was significant improvement in the UPDRS ADL and motor scores, but no change in mentation score. During the 6 months following physical rehabilitation, patients did not regularly exercise, and the UPDRS scores returned to baseline. We conclude that physical disability in moderately advanced PD objectively improves with a regular physical rehabilitation program, but this improvement is not sustained when normal activity is resumed.