Validity of Cardiovascular Data From Electronic Sources The Multi-Ethnic Study of Atherosclerosis and HealthLNK
Validity of Cardiovascular Data From Electronic Sources The Multi-Ethnic Study of Atherosclerosis and HealthLNK
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DOI：
10.1161/circulationaha.117.027436
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发表时间：
2017-09-26
期刊：
影响因子：
37.8
通讯作者：
Allen, Norrina B.
中科院分区：
文献类型：
--
作者：
Ahmad, Faraz S.;Chan, Cheeling;Allen, Norrina B.
背景技术背景：了解来自电子数据研究网络的数据的有效性对于国家研究计划和学习心血管护理的医疗保健系统至关重要。我们的目标是评估电子数据研究网络的协议的程度，通过标准化的研究方法收集的数据相比，在一个队列study.METHODS：我们连接个人层面的数据从梅萨（多种族研究的动脉粥样硬化），一个以社区为基础的队列，与HealthLNK，2006年至2012年的电子健康记录数据库从6芝加哥卫生系统。为了评估HealthLNK中血压与梅萨检查的相关性和一致性，以及HealthLNK中体重指数与梅萨的相关性和一致性，我们使用Pearson相关系数和Bland-Altman图。以梅萨中的诊断为判断标准，我们使用国际疾病分类第九次修订版代码和临床数据计算了HealthLNK对高血压、肥胖和糖尿病诊断的性能。我们还确定了潜在的心肌梗死，中风和心力衰竭事件在HealthLNK和比较他们的裁定事件在梅萨.RESULTS：在1164梅萨参与者参加了芝加哥现场中心，802（68.9%）参与者的数据在HealthLNK。与收缩压的相关性较低（0.39; P
BACKGROUND: Understanding the validity of data from electronic data research networks is critical to national research initiatives and learning healthcare systems for cardiovascular care. Our goal was to evaluate the degree of agreement of electronic data research networks in comparison with data collected by standardized research approaches in a cohort study.METHODS: We linked individual-level data from MESA (Multi-Ethnic Study of Atherosclerosis), a community-based cohort, with HealthLNK, a 2006 to 2012 database of electronic health records from 6 Chicago health systems. To evaluate the correlation and agreement of blood pressure in HealthLNK in comparison with in-person MESA examinations, and body mass index in HealthLNK in comparison with MESA, we used Pearson correlation coefficients and Bland-Altman plots. Using diagnoses in MESA as the criterion standard, we calculated the performance of HealthLNK for hypertension, obesity, and diabetes mellitus diagnosis by using International Classification of Diseases, Ninth Revision codes and clinical data. We also identified potential myocardial infarctions, strokes, and heart failure events in HealthLNK and compared them with adjudicated events in MESA.RESULTS: Of the 1164 MESA participants enrolled at the Chicago Field Center, 802 (68.9%) participants had data in HealthLNK. The correlation was low for systolic blood pressure (0.39; P