Carbon nanotube supported single phospholipid bilayer
Carbon nanotube supported single phospholipid bilayer
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DOI：
10.1021/la062038g
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发表时间：
2006-12-19
期刊：
影响因子：
3.9
通讯作者：
Majewski, Jaroslaw
中科院分区：
文献类型：
--
作者：
Gagner, Jennifer;Johnson, Hannah;Majewski, Jaroslaw
通过单层囊泡的融合，在微米级碳纳米管薄膜上形成了1-棕榈酰-2-油酰-sn-甘油基-3-磷酸胆碱（POPC）的单层双层膜。利用中子反射率（NR）研究了膜的结构。在Fe催化剂的存在下通过化学气相沉积（CVD）形成下面的CNT薄膜，然后与5 M硝酸反应以使膜亲水。我们证明，该平台支持均匀和连续的双层膜，在生物材料，生物传感器和生物物理学领域具有广阔的应用前景。
Single bilayer membranes of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) were formed on micron thin-films of hydrophilized carbon nanotubes (CNT) by fusion of small unilamellar vesicles. The structure of the membrane was investigated using neutron reflectivity (NR). The underlying thin film of CNT was formed by chemical vapor deposition (CVD) in the presence of Fe catalyst, followed by reaction with 5 M nitric acid to render the film hydrophilic. We demonstrate that this platform lends support to homogeneous and continuous bilayer membranes that have promising applications in the fields of biomaterials, biosensors, and biophysics.