PULMONARY-ARTERY PRESSURE CHANGES IN THE VERY-LOW-BIRTH-WEIGHT INFANT DEVELOPING CHRONIC LUNG-DISEASE
PULMONARY-ARTERY PRESSURE CHANGES IN THE VERY-LOW-BIRTH-WEIGHT INFANT DEVELOPING CHRONIC LUNG-DISEASE
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DOI：
10.1136/adc.68.3_spec_no.303
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发表时间：
1993-03-01
影响因子：
4.4
通讯作者：
WEINDLING, AM
中科院分区：
文献类型：
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作者：
GILL, AB;WEINDLING, AM
早产儿的肺动脉压与血流峰值时间/右室射血时间(TPV/RVET)呈负相关，故可无创地估计早产儿的肺动脉压。我们研究了54名出生后第1、2、3、7、14、21和28天的极低出生体重儿。34名婴儿发展为慢性肺部疾病(CLD)。20人没有，并充当了对照组。在校正了心率的TPV/RVET比率(TPV：RVET(C))后，在前14天，两组的TPV/RVET(C)比率逐渐上升，表明肺动脉压下降。在CLD组中，这种情况发生的速度明显较慢。从第14天到第28天，只有CLD组的这一比例显著下降，这表明肺动脉压升高。使用CLD作为终点，TPV：RVET(C)比率
Pulmonary artery pressure may be estimated non-invasively in the premature newborn infant because of its negative correlation with the time to peak velocity: right ventricular ejection time (TPV:RVET) ratio calculated from the pulmonary artery Doppler waveform. We studied 54 very low birthweight infants on days 1, 2, 3, 7, 14, 21, and 28 after birth. Thirty four infants developed chronic lung disease (CLD). Twenty did not and acted as controls. After correcting the TPV:RVET ratio for heart rate (TPV:RVET(c)), during the first 14 days the TPV:RVET(c) ratio rose progressively in both groups suggesting a fall in pulmonary artery pressure. This occurred at a significantly slower rate in the CLD group. From days 14 to 28 there was a significant fall in the ratio in the CLD group only, suggesting an increase in pulmonary artery pressure. Using CLD as the end point, a TPV:RVET(c) ratio