Factors associated with recent symptoms of an injection site infection or injury among people who inject drugs in three English cities
Factors associated with recent symptoms of an injection site infection or injury among people who inject drugs in three English cities
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DOI：
10.1016/j.drugpo.2013.11.012
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发表时间：
2014-03-01
影响因子：
4.4
通讯作者：
Ncube, F.
中科院分区：
文献类型：
--
作者：
Hope, V. D.;Hickman, M.;Ncube, F.
背景：注射吸毒者（PWID）存在注射部位感染和损伤的风险。研究了与这些问题最近症状有关的因素。方法：采用被调查者驱动的抽样方法招募PWID，进行计算机辅助访谈并提供干血斑样本。采用logistic回归对体重数据进行检验。结果：855名参与者的平均年龄为32岁，其中25%为女性。在之前的28天里，94%的人注射过海洛因，50%注射过可卡因；41%注射在手臂，47%注射在腹股沟。使用过的针头/注射器的传递率为9.7%，接收率为8.0%。在之前的28天内，21%的患者报告出现红肿和压痛，6.1%的患者报告出现脓肿，5.2%的患者报告在注射部位出现溃疡/开放性伤口；四分之一（24%）的人报告了一种或多种这种情况。一系列因素与这些症状有关；所有这三种症状都与更频繁的注射和使用多个注射部位有关；其中两种症状还与最近服药过量和使用特定注射部位有关。结论：注射部位感染和损伤在PWID中很常见，需要采取有针对性的干预措施来降低风险。爱思唯尔B.V.版权所有
Background: People who inject drugs (PWID) are at risk of injection site infections and injuries. The factors associated with recent symptoms of these problems are examined.Method: PWID recruited using respondent driven sampling, underwent a computer-assisted interview and provided a dried-blood spot sample. Weight data were examined using logistic regression.Results: The mean age of the 855 participants was 32 years, and 25% were women. During the preceding 28 days, 94% had injected heroin and 50% crack-cocaine; with 41% injecting into their arms and 47% their groin. The passing on of used needles/syringes was reported by 9.7% and receiving by 8.0%. During the preceding 28 days, 21% reported having redness, swelling and tenderness, 6.1% an abscess, and 5.2% a sore/open wound at an injection site; with a quarter (24%) reporting one or more of these. A range of factors were associated with these symptoms; all three symptoms were associated with more frequent injection and the use of multiple injection sites; two of the symptoms were also associated with having recently overdosed and the use of particular injection sites.Conclusions: Injection site infections and injuries are common among PWID and targeted interventions are needed to reduce risk. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.