Acquired carnitine abnormalities in critically ill children
Acquired carnitine abnormalities in critically ill children
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DOI：
10.1007/s004310050732
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发表时间：
1997-11-01
影响因子：
3.6
通讯作者：
Lambert, M
中科院分区：
文献类型：
--
作者：
Proulx, F;Lacroix, J;Lambert, M
为了表征肉碱在代谢应激中的作用，我们前瞻性地测定了28名无任何已知继发性肉碱缺乏相关疾病的危重儿童入院时血浆和尿液中的肉碱谱，分别为入院第2、5、10和15天。超过25%的血浆和50%的尿肉碱测量异常；96%（27/28）的患者至少有一次血浆肉碱值异常[+2 SD]。三个孩子的[
In order to characterize the role of carnitine during metabolic stress, we prospectively determined carnitine profiles in plasma and urine on admission, days 2, 5, 10 and 15, among 28 critically ill children free of any known conditions associated with secondary carnitine deficiency. More than 25% of plasma and 50% of urinary carnitine measurements were abnormal; 96% (27/28) of patients displayed on at least one occasion an abnormal [+2 SD] carnitine value in plasma. Three children had extremely low [