Optical coherent tomography features of Malattia leventinese
Optical coherent tomography features of Malattia leventinese
复制标题
DOI：
10.1016/j.ajo.2005.09.001
复制
发表时间：
2006-02-01
影响因子：
4.2
通讯作者：
Soubrane, G
中科院分区：
文献类型：
--
作者：
Souied, EH;Leveziel, N;Soubrane, G
目的：Malattia leventinese（ML）是一种遗传性黄斑变性，其特征是存在大的中央旁玻璃疣和小的放射状玻璃疣。我们的目的是描述光学相干断层扫描（OCT）观察ML.DESIGN：前瞻性观察病例series.METHODS：从5例ML患者年龄27至44岁的10只眼睛被前瞻性纳入。最佳矫正视力，眼底彩色摄影的视网膜，和OCT进行在每个patient.RESULTS：OCT显示视网膜色素上皮细胞-布鲁赫膜复合物，与局部圆顶，形隆起的高反射增厚。玻璃疣上方视网膜厚度为221 ~ 292 μ m，平均260 μ m。中心凹厚度范围为72 - 200 μ m（平均144 μ m）。结论：大的中央旁玻璃疣表现为视网膜色素上皮-Bruch复合体增厚或视网膜色素上皮-Bruch复合体局部有限升高，两者均与神经感觉视网膜的保存有关。
PURPOSE: Malattia leventinese (ML) is an inherited macular degeneration characterized by the presence of large paracentral and small radial drusen. Our purpose was to describe optical coherent tomography (OCT) features observed in ML.DESIGN: Prospective observational case series.METHODS: Ten eyes from five patients with ML aged 27 to 44 years were prospectively included. Best-corrected visual acuity, fundus color photography of the retina, and OCT were performed in each patient.RESULTS: OCT revealed a hyperreflective thickening of the retinal pigment epithelium-Bruch membrane complex, associated with localized dome,shaped elevations. Retinal thickness above the drusen ranged from 221 to 292 mu m (mean 260 mu m). Foveal thickness ranged from 72 to 200 mu m (mean 144 mu m)CONCLUSIONS: The large paracentral drusen presented either as a thickening of the retinal pigment epitheliumBruch complex or as local limited elevation of retinal pigment epithelium-Bruch complex, both associated with preservation of the neurosensory retina.