Multisite Recording of Local Field Potentials in Awake, Free-Moving Mice
Multisite Recording of Local Field Potentials in Awake, Free-Moving Mice
复制标题
清醒、自由移动小鼠局部场电位的多点记录
DOI：
10.1007/978-1-4939-8609-5_14
复制
发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Li A.
中科院分区：
文献类型：
--
作者：
Mao X;Cao T;Li A.
局部场电位振荡在神经科学研究中至关重要，因为它们与许多与感觉、运动、学习和认知相关的大脑活动有关。在清醒的动物中，同时从不同的大脑区域对lfp进行多位点记录是非常重要的，因为它们可以提供关于大脑区域如何相互合作以执行特定功能的重要信息。在这里，我们描述了一种方法，可以记录来自清醒自由运动小鼠的六个嗅觉相关区域（嗅球、梨状皮质和海马）的LFP信号。如果任何两个记录点之间的最短距离大于2毫米，这种方法可以记录多达16个不同的大脑区域。
Oscillations of local field potentials (LFPs) are crucial in neuroscience studies since they are correlated with many brain activities related to sense, motor, learning, and cognition. Multisite recording of LFPs from different brain areas in awake animals simultaneously is extremely important because they could provide important information on how the brain areas cooperate with each other to perform a specific function. Here, we describe a method that could record LFP signals from six olfactory-related areas (both olfactory bulbs, both piriform cortices, and both hippocampi) in awake free-moving mice. This method could be developed to record up to 16 different brain areas if the shortest distance between any two recording sites is larger than 2 mm.