Off-channel effect of high-frequency overstimulation on duration tuning of low-frequency inferior colliculus neurons in guinea pigs

Off-channel effect of high-frequency overstimulation on duration tuning of low-frequency inferior colliculus neurons in guinea pigs
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高频过度刺激对豚鼠低频下丘神经元持续时间调节的通道外效应

DOI:
10.3109/00016480902856562
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发表时间:
2009-01
影响因子:
1.4
通讯作者:
殷善开
殷善开
中科院分区:
医学4区
文献类型:
--
作者:
殷善开

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Conclusion. High-frequency overstimulation can cause the loss of duration selectivity in low-frequency inferior colliculus neurons in guinea pigs. Objective. To investigate the effect of high-frequency overstimulation on duration tuning in low-frequency inferior colliculus neurons in guinea pigs. Materials and methods. Duration tuning pattern was recorded by measuring the spikes of single neurons in response to the best frequency (BF) of different durations. The effect of high-frequency overstimulation was verified by comparing the responses before and after the tone exposure. Results. In total, 40 duration-tuned neurons were successfully recorded before and after the tone exposure. After the high-frequency tone trauma, a total of 29 neurons (72.5%) became non-duration-tuned.
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