SIMPLE HYPOTHERMIC PRESERVATION FOR TRANSPORTING HUMAN LIVERS LONG DISTANCES FOR TRANSPLANTATION

SIMPLE HYPOTHERMIC PRESERVATION FOR TRANSPORTING HUMAN LIVERS LONG DISTANCES FOR TRANSPLANTATION
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长距离运输人类肝脏进行移植的简单低温保存

DOI:
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发表时间:
1977
期刊:
影响因子:
6.2
通讯作者:
R. Williams
R. Williams
中科院分区:
医学2区
文献类型:
--
作者:
Wallace Wj;Calne Ry;B. Herbertson;Baker Pg;Darrin P. Smith;J. Underwood;Kostakis Aj;R. Williams

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自1973年以来,剑桥-国王学院医院肝脏移植计划中的12名患者接受了捐赠者的肝脏,捐赠者死于距离剑桥移植中心相当远的医院。将这些肝脏从35英里运送到110英里的保存方法是用血浆蛋白组分冲洗灌流,然后在冰中低温储存。缺血时间从2小时和42分钟到4小时和22分钟不等。所有受者术后移植物功能良好或优良,12例受者中6例存活,最长存活29个月。该保存技术简单,易于携带,并提供了可靠的4小时保存人类肝脏。
Since 1973, 12 patients in the Cambridge-King's College Hospital liver transplant programme have received livers from donors dying in hospitals considerable distances from the transplant centre in Cambridge. The method of preservation used to transport these livers from 35 to 110 miles was flush perfusion with plasma protein fraction and hypothermic storage in ice. The ischaemia times ranged from 2 hr and 42 min to 4 hr and 22 min. All of the recipients had good or excellent postoperative function of the grafts and 6 of the 12 recipients are alive, the longest survival being 29 months. The preservation technique is simple and easily portable and has given reliable 4-hr preservation of the human liver.