Patient-Reported Outcomes of Surgery of Non-Small Cell Lung Cancer: Evaluation Based on the Questionnaires of Anti-Aging Quality of Life and the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire
Patient-Reported Outcomes of Surgery of Non-Small Cell Lung Cancer: Evaluation Based on the Questionnaires of Anti-Aging Quality of Life and the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire
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非小细胞肺癌患者报告的手术结果：基于抗衰老生活质量调查问卷和欧洲癌症研究与治疗组织生活质量调查问卷的评估
DOI：
10.4236/ss.2017.85024
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Kunihide Nakamura
中科院分区：
文献类型：
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作者：
T. Ayabe;M. Tomita;N. Nose;T. Asada;Kunihide Nakamura
背景：患者报告的开胸手术后生活质量(QOL)的结果尚未被研究。确定手术患者的生理和心理变化对医务人员来说是非常重要的。采用患者自评问卷对手术患者满意度和整体健康变化进行评估。材料和方法：2007年7月至2008年4月，26例非小细胞肺癌患者接受手术切除。采用欧洲癌症研究与治疗组织生活质量问卷(EORTC QLQ-C30)和抗衰老生活质量测评(AA-QOL)两种问卷调查方法对患者的生活质量结果进行评估。EORTC QLQ-C30由五个领域(生理、角色、认知、情感和社会功能)和总体生活质量组成。AA-QOL包括51个条目；30个身体症状和21个精神症状，涉及老年人和老龄化人口。患者在两个不同的时间回答了这两个问卷，即术前(基线)和术后(手术后2周)。将获得的这些评分数据进行平均化，并在术前和术后的两个积分之间进行比较。结果：对于EORTC QLQ-C30的结果，术后躯体和社会功能明显恶化。相比之下，手术后整体生活质量明显改善。术后症状较术前明显加重，其中“恶心呕吐”、“疼痛”和“食欲不振”三项症状明显加重。对于AA-QOL的结果，术后躯体症状(肌肉疼痛/僵硬、心悸、呼吸困难、感觉不好、食欲不振、咳嗽和咳痰)明显恶化。在精神症状方面，两组无显著差异。结论：从术后生活质量的变化来看，躯体症状比精神症状更严重。明确肺癌患者围手术期生活质量的健康变化，对于多学科协作具有重要意义，它将为患者提供适当的护理和治疗，并为患者做出手术治疗的决策提供有用的信息。
Background: Patient-reported outcomes of the quality of life (QOL) after an open thoracotomy have not been studied. To determine the physical and mental changes in surgical patients is very important for medical staffs. The surgical patient’s satisfaction and overall healthy changes were evaluated by the patient-self assessment questionnaires. Materials and Methods: From July 2007 to April 2008, 26 patients with non-small cell lung cancer (NSCLC) underwent surgical resection. The outcome of the QOL was evaluated by using two kinds of questionnaire surveys from the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the anti-aging QOL assessment (AA-QOL). The EORTC QLQ-C30 consisted of five domains (physical, role, cognitive, emotional, and social functionings) and global QOL. The AA-QOL contained 51 items; 30 physical and 21 mental symptoms regarding the elderly and the aging population. The patients replied to the two questionnaires at two different times, i.e., at pre-surgery (baseline) and at post-surgery (2 weeks after the operation). The obtained data of these scores were averaged and compared between the two points of the pre-surgery and post-surgery. Results: Regarding the outcomes of the EORTC QLQ-C30, the physical and social functioning became significantly worse after the surgery. In contrast, the global QOL significantly became better after the surgery. For the symptom at post-surgery, three of which were “nausea and vomiting”, “pain”, and “appetite loss”, became significantly worse compared to those at pre-surgery. Regarding the outcomes of the AA-QOL, the physical symptoms (muscular pain/stiffness, palpitations, dyspnea, no feeling of good health, anorexia, and coughing and sputum) became significantly worse after the surgery. Regarding the mental symptoms, there were no significant differences. Conclusions: Regarding the outcomes based on the changes in the QOL after surgery, the physical symptoms became worse compared to the mental symptoms. To clarify the perioperative healthy changes of the QOL reported by patients with lung cancers is very important for multidisciplinary teamwork, which should play a role in providing the appropriate care and treatment and useful information for a preoperative patient’s decision making of receiving surgical treatment.
DOI：
10.1016/j.jtcvs.2015.05.057
发表时间：
2015-09
期刊：
The Journal of thoracic and cardiovascular surgery
影响因子：
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作者：
Fagundes CP;Shi Q;Vaporciyan AA;Rice DC;Popat KU;Cleeland CS;Wang XS
通讯作者：
Wang XS