Hypothetical and Real Choice Differentially Activate Common Valuation Areas
Hypothetical and Real Choice Differentially Activate Common Valuation Areas
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DOI：
10.1523/jneurosci.1583-10.2011
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发表时间：
2011-01-12
影响因子：
5.3
通讯作者：
Camerer, Colin F.
中科院分区：
文献类型：
--
作者：
Kang, Min Jeong;Rangel, Antonio;Camerer, Colin F.
对预期行为的假设性报告通常用于对真实的选择得出结论。决策神经科学中的一个基本问题是，在假设的和真实的决策中，是否执行了相同类型的估值和选择计算。我们调查了这个问题，使用功能磁共振成像，而人类受试者作出真实的和假设的选择购买消费品。我们发现，在这两种类型的决策中，眶额皮质和腹侧纹状体的共同区域的活动与商品刺激值的行为测量相关。此外，我们发现，在这些地区的活动更强的刺激值信号的反应在真实的选择条件。研究结果表明，真实的和假设的选择之间的差异主要是由于内侧眶额皮质和腹侧纹状体的价值计算的变化，而不是由于使用不同的估值系统，或计算更强的刺激值信号的假设条件。
Hypothetical reports of intended behavior are commonly used to draw conclusions about real choices. A fundamental question in decision neuroscience is whether the same type of valuation and choice computations are performed in hypothetical and real decisions. We investigated this question using functional magnetic resonance imaging while human subjects made real and hypothetical choices about purchases of consumer goods. We found that activity in common areas of the orbitofrontal cortex and the ventral striatum correlated with behavioral measures of the stimulus value of the goods in both types of decision. Furthermore, we found that activity in these regions was stronger in response to the stimulus value signals in the real choice condition. The findings suggest that the difference between real and hypothetical choice is primarily attributable to variations in the value computations of the medial orbitofrontal cortex and the ventral striatum, and not attributable to the use of different valuation systems, or to the computation of stronger stimulus value signals in the hypothetical condition.