Whole-body hybrid PET with 18F-FDG in the staging of non-Hodgkin's lymphoma.
Whole-body hybrid PET with 18F-FDG in the staging of non-Hodgkin's lymphoma.
复制标题
全身混合 PET 与 18F-FDG 在非霍奇金淋巴瘤分期中的应用。
DOI：
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复制
发表时间：
2001
影响因子：
9.3
通讯作者：
T. Nishimura
中科院分区：
文献类型：
--
作者：
M. Tatsumi;H. Kitayama;H. Sugahara;N. Tokita;H. Nakamura;Y. Kanakura;T. Nishimura
未标记
双探头γ照相机PET（混合PET）是18F-FDG肿瘤成像的新方法。本研究旨在阐明全身FDG混合PET与专用摄像机PET（专用PET）相比在非霍奇金淋巴瘤（NHL）分期中的可行性，并将两种FDG研究的结果与CT和67 Ga扫描作为常规成像研究（CIS）的结果进行比较。
方法
对30例NHL患者进行了前瞻性评价。基于最终总体临床评价，将涉及部位检测和分期的成像研究结果相互比较，并与参比标准品的结果进行比较。
结果
在总共206个部位中，全身FDG混合PET和专用PET分别检测到159个部位（77.2%）和179个部位（86.9%）。混合PET单独遗漏的20个部位中有18个病变< 1.5 cm。除2例患者外，两项FDG研究均提供了一致的分期结果。另一方面，CIS检测到206个位点中的164个（79.6%），其中137个也被混合PET检测到。混合PET检测到另外22个未被CIS发现的位点，而CIS检测到另外27个位点。混合PET和CIS在19例患者中提供了一致的分期结果。混合PET在另外5名患者中正确分期NHL，而CIS仅在另外1名患者中正确分期NHL。
结论
全身FDG混合PET似乎是一种准确的NHL分期方法。尽管与专用PET相比其图像质量较差，但混合PET提供的NHL分期结果与专用PET相当。混合PET也产生了与CIS相当的结果。然而，全身FDG混合PET目前不足以作为NHL分期的单一模式，并且是CT的补充。
UNLABELLED
PET with a double-head gamma camera (hybrid PET) is a new approach to tumor imaging with 18F-FDG. This study was conducted to clarify the feasibility of whole-body FDG hybrid PET in the staging of non-Hodgkin's lymphoma (NHL) in comparison with PET with a dedicated camera (dedicated PET) and to compare the results of both FDG studies with those of CT and 67Ga scanning as conventional imaging studies (CIS).
METHODS
Thirty patients with NHL were prospectively evaluated. The results of the imaging studies regarding detection of the sites involved and staging were compared with each other and with those of the reference standard based on the final overall clinical evaluation.
RESULTS
Of the total of 206 sites, whole-body FDG hybrid PET and dedicated PET detected 159 sites (77.2%) and 179 sites (86.9%), respectively. Eighteen of the 20 sites missed by hybrid PET alone consisted of lesions < 1.5 cm. Both FDG studies provided concordant staging results in all but 2 patients. CIS, on the other hand, detected 164 (79.6%) of the 206 sites, 137 of which were also detected by hybrid PET. Hybrid PET detected an additional 22 sites not found by CIS, whereas CIS detected 27 additional sites. Hybrid PET and CIS provided concordant staging results in 19 patients. Hybrid PET correctly staged NHL in 5 additional patients, whereas CIS correctly staged NHL in only 1 additional patient.
CONCLUSION
Whole-body FDG hybrid PET appeared to be an accurate method of staging NHL. Despite its poorer image quality compared with dedicated PET, hybrid PET provided NHL staging results comparable with those of dedicated PET. Hybrid PET also yielded results comparable with those of CIS. However, whole-body FDG hybrid PET is currently inadequate as a single modality for staging NHL and is complementary to CT.
全身 FDG-PET 成像用于霍奇金病和淋巴瘤的分期。
DOI：
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发表时间：
1997
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Hoh,CK;Glaspy,J;Rosen,P;Dahlbom,M;Lee,SJ;Kunkel,L;Hawkin,RA;Maddahi,J;Phelps,ME
通讯作者：
Phelps,ME
DOI：
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发表时间：
1981
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Larson,SM;Weiden,PL;Grunbaum,Z;Kaplan,HG;Rasey,JS;Graham,MM;Sale,GE;Harp,GD;Williams,DL
通讯作者：
Williams,DL