Obesity, albuminuria, and urinalysis findings in US young adults from the Add Health Wave III study
Obesity, albuminuria, and urinalysis findings in US young adults from the Add Health Wave III study
复制标题
DOI：
10.2215/cjn.00540107
复制
发表时间：
2007-11-01
影响因子：
9.8
通讯作者：
Jennette, J. Charles
中科院分区：
文献类型：
--
作者：
Ferris, Maria;Hogan, Susan L.;Jennette, J. Charles
背景和目的：肥胖与成人肾脏疾病有关。本研究旨在评估年轻人中肥胖与肾脏疾病早期标志物蛋白尿的关系。设计、环境、参与者和测量：在Add Health Wave III队列（2001年至2002年）中测量尿液分析（n = 9371）、白蛋白与肌酐比（n = 4463）和体重指数（kg/m(2)），这是一个多种族的年轻成年人样本，随访了大约6年。多因素logistic回归模拟了性别特异性蛋白尿与体重指数的关系，并根据样本重量、性别、种族、民族和糖尿进行了调整。结果：蛋白尿0.8%，血尿4.6%，血尿合并蛋白尿0.2%，糖尿1.5%。蛋白尿患病率为4.4%。蛋白尿患者的平均体重指数高于无蛋白尿患者。身体质量指数在25到
Background and objectives: Obesity has been associated with kidney disease in adults. This study was designed to evaluate the association of obesity with an early marker of kidney disease, albuminuria, among young adults.Design, setting, participants, & measurements: Urinalysis (n = 9371), albumin-to-creatinine ratio (n = 4463), and body mass index (kg/m(2)) were measured in the Add Health Wave III cohort (2001 to 2002), a multiethnic sample of young adults followed for approximately 6 yr. Multivariate logistic regression modeled the association of sex-specific albuminuria with body mass index, adjusted for sample weights, sex, race, ethnicity, and glycosuria.Results: Urinalysis revealed that 0.8% had proteinuria, 4.6% had hematuria, 0.2% had combined hematuria and proteinuria, and 1.5% had glycosuria. Albuminuria prevalence was 4.4%. Mean body mass index was higher among those with albuminuria compared with those without. There were no associations between body mass index categories of 25 to