Challenge of ex vivo-stimulated CD4(+)CD25(+) regulatory T cell-mediated alloantigen-specific immunosuppression by murine cardiac transplantation
Challenge of ex vivo-stimulated CD4(+)CD25(+) regulatory T cell-mediated alloantigen-specific immunosuppression by murine cardiac transplantation
复制标题
鼠心脏移植离体刺激CD4( )CD25( )调节性T细胞介导的同种异体抗原特异性免疫抑制的挑战
DOI：
10.1016/j.trim.2016.12.005
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发表时间：
2017
影响因子：
1.5
通讯作者：
and T. Kato.
中科院分区：
文献类型：
--
作者：
Hori;T.;S. Uemoto;K. Saito;K. Kuribayashi;Y. Hori;and T. Kato.
同种异体抗原免疫后通过紫外线照射在体内诱导的同种异体抗原特异性CD 4（+）调节性T细胞需要白细胞介素-10进行诱导和激活，并灵活地介导同种异体排斥反应的旁观者免疫抑制。
Alloantigen-specific CD4 (+) regulatory T cells induced in vivo by ultraviolet irradiation after alloantigen immunization require interleukin-10 for their induction and activation, and flexibly mediate bystander immunosuppression of allograft rejection.