The role of pain in quitting among human immunodeficiency virus (HIV)-positive smokers enrolled in a smoking cessation trial.
The role of pain in quitting among human immunodeficiency virus (HIV)-positive smokers enrolled in a smoking cessation trial.
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DOI：
10.1080/08897077.2017.1291466
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发表时间：
2017-07
期刊：
影响因子：
3.5
通讯作者：
Vidrine DJ
中科院分区：
文献类型：
--
作者：
Aigner CJ;Gritz ER;Tamí-Maury I;Baum GP;Arduino RC;Vidrine DJ
人体免疫机能丧失病毒/后天免疫机能丧失综合症（艾滋病毒/艾滋病;艾滋病毒/艾滋病感染者）的吸烟率至少是一般人口的两倍。与疼痛和吸烟的相互作用模型一致，吸烟的疼痛感染者可能使用吸烟作为应对疼痛的手段，从而对戒烟构成潜在障碍。本研究的目的是更好地了解疼痛与474名参加手机戒烟试验的艾滋病毒阳性成年人戒烟的关系。参与者被随机分配到常规护理（戒烟建议和自助材料）或11次手机戒烟治疗。在3个月治疗结束时以及6个月和12个月随访时收集疼痛（由医学结局研究-HIV健康调查（MOS-HIV）评估）和点流行率禁欲。通过呼出的一氧化碳（CO）水平<7 ppm对自我报告的禁欲进行生化验证。使用多水平模型的二元结果数据，作者检查了疼痛和禁欲之间的关系，从治疗结束到12个月的随访。与作者的假设一致，在控制年龄、性别、基线疼痛、尼古丁依赖和治疗组的情况下，疼痛减轻与24小时（β = 0.01，t（651）= 2.53，P = 0.01）和7天（β = 0.01，t（651）= 2.35，P = 0.02）点戒烟率的可能性更高相关。未观察到疼痛×治疗组相互作用。这些结果可以帮助我们更好地识别在戒烟治疗中复发风险更大的PLWHA。未来的研究可能会检查更全面的戒烟治疗的有效性，其中包括对吸烟并具有高疼痛和症状负担的PLWHA的疼痛管理方面。
Smoking rates among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS; PLWHA) are at least twice as high as rates in the general population. Consistent with the reciprocal model of pain and smoking, PLWHA with pain who smoke may use smoking as a means of coping with pain, thus presenting a potential barrier to quitting. The aim of this study is to better understand how pain relates to smoking cessation among 474 HIV-positive adults enrolled in a cell phone–delivered smoking cessation trial. Participants were randomly assigned to usual care (cessation advice and self-help materials) or 11 sessions of cell phone–delivered smoking cessation treatment. Pain, as assessed by the Medical Outcomes Study-HIV Health Survey (MOS-HIV), and point prevalence abstinence were collected at the 3-month treatment end and at 6- and 12-month follow-ups. Self-reported abstinence was biochemically verified by expired carbon monoxide (CO) level of <7 ppm. Using multilevel modeling for binary outcome data, the authors examined the relationship between pain and abstinence, from treatment end through the 12-month follow-up. Consistent with the authors’ hypothesis, less pain was associated with greater likelihood of 24-hour (β = .01, t(651) = 2.53, P = .01) and 7-day (β = .01, t(651) = 2.35, P = .02) point prevalence abstinence, controlling for age, gender, baseline pain, nicotine dependence, and treatment group. No pain × treatment group interaction was observed. These results can help us to better identify PLWHA at greater risk for relapse in smoking cessation treatment. Future research may examine the effectiveness of more comprehensive smoking cessation treatment that incorporates aspects of pain management for PLWHA who smoke and have high pain and symptom burden.
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