Neuronal responses from beyond the classic receptive field in V1 of alert monkeys
Neuronal responses from beyond the classic receptive field in V1 of alert monkeys
复制标题
警觉猴 V1 区经典感受野之外的神经元反应
DOI：
--
复制
发表时间：
2001
影响因子：
2
通讯作者：
C. Wehrhahn
中科院分区：
文献类型：
--
作者：
Wu Li;P. Thier;C. Wehrhahn
抽象的。初级视觉皮层 (V1) 神经元对经典感受野 (CRF) 内部刺激的反应可以通过 CRF 外部的刺激进行调节。我们最近报道，大多数 V1 神经元对 CRF 中心线的反应受到大的周围刺激的抑制，并且这种调节是刺激选择性的。在这里，我们报告说，警觉的猴子中很大一部分 V1 神经元直接对 CRF 之外的刺激做出反应，潜伏期很长，选择性也大大降低。当单独呈现周围刺激时，在测试的 153 个单单元或多单元中可以区分出三种反应模式：（1）31.4％没有显着反应； (2) 50.3%表现出明显高于自发活动的兴奋反应。这些响应的平均延迟约为 145 毫秒，是中心响应的 2-3 倍； (3) 18.3% 的人在刺激发生后表现出自发活动受到抑制。发现直接环绕响应对于上下文线的方向仅具有弱选择性，并且对于测试的其他上下文模式没有选择性。虽然 CRF 内对刺激的反应爆发不会因刺激持续时间从 500 毫秒减少到 50 毫秒而受到影响，但后期的兴奋性周围反应实际上被消除了。我们认为，单独对 CRF 外刺激的晚期兴奋性周围反应是来自较高皮质区域的反馈的反映，并且可能有助于减少 V1 细胞的背景抑制。这可能会在图形与背景的分离中发挥作用。
Abstract. Responses of primary visual cortex (V1) neurons to stimuli inside the classic receptive field (CRF) can be modulated by stimuli outside the CRF. We recently reported that responses of most V1 neurons to a line in the CRF center are inhibited by large surround-stimuli and that this modulation is stimulus selective. Here we report that a significant proportion of V1 neurons in alert monkeys respond directly to stimuli outside the CRF with very long latency and much reduced selectivity. When surround stimuli are presented alone, three response patterns can be distinguished in 153 single- or multiunits tested: (1) 31.4% have no significant response; (2) 50.3% show excitatory responses that are significantly higher than spontaneous activity. The average latency of these responses is about 145 ms, 2–3 times longer than center responses; (3) 18.3% show suppressed spontaneous activity after stimulus onset. The direct surround responses are found to be only weakly selective for the orientation of contextual lines, and not selective for other contextual patterns tested. While the outburst of responses to stimuli within the CRF is not affected by reducing stimulus duration from 500 ms to 50 ms, late excitatory surround responses are virtually eliminated. We propose that the late excitatory surround responses to extra-CRF stimulation alone are the reflection of feedback from higher cortical areas and may contribute to reduced contextual inhibition of cells in V1. This could play a role in figure-ground segregation.
DOI：
10.1073/pnas.89.17.8366
发表时间：
1992-09-01
影响因子：
11.1
作者：
PETTET, MW;GILBERT, CD
通讯作者：
GILBERT, CD
影响因子：
2.5
作者：
KNIERIM, JJ;VANESSEN, DC
通讯作者：
VANESSEN, DC