TEMPORAL PATTERNS OF DISCHARGE OF PYRAMIDAL TRACT NEURONS DURING SLEEP + WAKING IN MONKEY
TEMPORAL PATTERNS OF DISCHARGE OF PYRAMIDAL TRACT NEURONS DURING SLEEP + WAKING IN MONKEY
复制标题
DOI：
10.1152/jn.1964.27.2.152
复制
发表时间：
1964-01-01
影响因子：
2.5
通讯作者：
EVARTS, EV
中科院分区：
文献类型：
--
作者：
EVARTS, EV
完整的，未经麻醉的猴子的锥体道（PT）神经元通过对刺激髓质金字塔刺激的反应来鉴定出一个未经动心的猴子，并记录其活性在没有运动（W）的情况下醒来时，在EGEG慢波的情况下（W）睡觉（w）（w） ），并以低压快速脑电图活性（S-LVF）睡眠。在W期间，PT神经元显示正常排出，没有高频爆发和沉默周期。在S期间，出现爆发和沉默时期，活动的数量下降。在S-LVF期间，长度的爆发和中间的静音增加，排放量增加。 W和S-LVF期间的总活性大致相同。建议在S和S-LVF期间高频突发的发生可能是由于某些频率限制机制的有效性降低而导致的，该机制在W期间起作用。这与兴奋驱动的减少有关。当W期间发生运动时，所有的活动量大于任何其他时间，但不会发生高频爆发。因此，S-LVF期间的放电模式与有或没有运动的过程中的醒来完全不同。
Pyramidal tract (PT) neurons in the precentral gyrus of the intact, unanesthetized monkey were identified by antidromic responses to stimulation of the medullary pyramid and their activity was recorded during waking in the absence of movement (W), sleep with EEG slow waves (S), and sleep with low voltage fast EEG activity (S-LVF). During W, PT neurons show regular discharge with an absence of high frequency bursts and periods of silence. During S, bursts and periods of silence appear, and over-all amount of activity falls. During S-LVF, both bursts and intervening periods of silence increase in length, and over-all amount of discharge increases. Total amount of activity during W and S-LVF is approximately the same. It is suggested that the occurrence of high frequency bursts during S and S-LVF may result from a reduction in the effectiveness of some frequency-limiting mechanism which acts to stabilize discharge during W. The decrease in over-all amount of activity with S indicates that S is associated with a reduction in excitatory drive. When movement occurs during W, over-all amount of activity is greater than at any other time, but high frequency bursts do not occur. Thus, the pattern of discharge during S-LVF is entirely different from that during waking, either with or without movement.