Giant protruding high grade undifferentiated pleomorphic sarcoma arising in a keloid scar on the abdominal wall.
Giant protruding high grade undifferentiated pleomorphic sarcoma arising in a keloid scar on the abdominal wall.
复制标题
巨大突出的高级未分化多形性肉瘤，产生于腹壁瘢痕疙瘩中。
DOI：
10.1155/2020/4898965
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Yonemoto T.
中科院分区：
文献类型：
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作者：
Kinoshita H;Tsukanishi T;Ishii T;Kamoda H;Hagiwara Y;Orita S;Inage K;Hirosawa N;Ohtori S;Yonemoto T.
未分化多形性肉瘤（UPS）是一种高级别、侵袭性、软组织肉瘤，通常是致命的。尽管有报道描述了肉瘤和皮肤病变如烧伤、辐射和创伤的相关性，但据我们所知，瘢痕疙瘩中UPS的发展尚未报道。在此，我们提出了一个76岁的妇女谁经历了子宫内膜癌手术，5年前的情况。她提出了一个突出的病变，是连续的瘢痕疙瘩疤痕在腹壁上。肿瘤临床表现为恶性，因为它突出，在三周内大小增加一倍，达到约6 × 6 × 2 cm。由于肿瘤被诊断为UPS后，病理评估针活检，广泛切除。术中肿瘤明显与瘢痕疙瘩相连，突出并有蒂于体外，未侵犯腹腔。切除肿瘤的组织学检查显示UPS的证据，没有子宫内膜癌转移的怀疑。术后6个月无复发、转移或其他并发症。目前的病例研究提醒我们，瘢痕疙瘩可能会导致高级别肉瘤，如UPS，需要仔细随访。
Undifferentiated pleomorphic sarcoma (UPS) is a high‐grade, aggressive, soft tissue sarcoma that is often fatal. Although there are reports describing associations of sarcoma and skin lesions such as burns, radiation, and trauma, to our knowledge, UPS development in a keloid scar has not been reported. Herein, we present the case of a 76‐year‐old woman who had undergone surgery for endometrial cancer, 5 years before. She presented with a protruding lesion that was continuous to a keloid scar on the abdominal wall. The tumor appeared clinically malignant as it was protruding and doubled in size within three weeks, reaching approximately 6 × 6 × 2 cm. Since the tumor was diagnosed as UPS after pathological evaluation by needle biopsy, wide resection was performed. Intraoperatively, the tumor was apparently continuous to the keloid, protruding and pedunculated outside the body, and had not invaded the abdominal cavity. Histopathological examination of the resected tumor showed evidence of UPS and no suspicion of metastasis of endometrial cancer. No recurrence, metastases, or other complications were noted 6 months after surgery. The current case study reminds us that keloids may cause high‐grade sarcoma such as UPS, and careful follow‐up is required.