Characterizing the HIV Prevention and Care Continua in a Sample of Transgender Youth in the U.S.

Characterizing the HIV Prevention and Care Continua in a Sample of Transgender Youth in the U.S.
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DOI:
10.1007/s10461-017-1938-8
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发表时间:
2017-12
期刊:
影响因子:
4.4
通讯作者:
Harper GW
Harper GW
中科院分区:
医学2区
文献类型:
--
作者:
Reisner SL;Jadwin-Cakmak L;White Hughto JM;Martinez M;Salomon L;Harper GW

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在美国,跨性别者和其他性别少数群体(TG)青年是艾滋病预防和治疗中未得到充分研究的高危群体。本研究旨在描述2015年7月至12月在美国14个城市招募的181名年龄在16-24岁的性活跃TG(平均年龄为20.7岁,76.8%为跨性别女性,69.1%为有色人种青年)的不同样本中HIV预防和护理的连续性特征。总体而言,30.9%的人报告携带艾滋病毒,其中71.4%的人接受抗逆转录病毒治疗(ART), 55.0%的人坚持服药;65.6%的人被病毒抑制。在多变量模型中,医学性别肯定与较低的病毒抑制几率相关。艾滋病护理中的医学性别肯定和耻辱各自与错过艾滋病护理预约的几率升高独立相关。在没有感染艾滋病毒的高危TG青年中,只有8.2%获得了暴露前预防(PrEP)。TG青年需要早期的生物行为预防和治疗干预。
In the U.S., transgender and other gender minority (TG) youth are an at-risk group understudied in HIV prevention and treatment. This study sought to characterize the HIV prevention and care continua in a diverse sample of 181 sexually-active TG ages 16–24 years (mean age = 20.7 years; 76.8% trans feminine; 69.1% youth of color) recruited July–December 2015 in 14 U.S. cities. Overall, 30.9% reported living with HIV, of which 71.4% were on antiretroviral therapy (ART) and 55.0% were medication adherent; 65.6% were known to be virally suppressed. In multivariable models, medical gender affirmation was associated with lower odds of viral suppression. Medical gender affirmation and stigma in HIV care were each independently associated with elevated odds of having missed HIV care appointments. Among at-risk TG youth not living with HIV, only 8.2% had accessed pre-exposure prophylaxis (PrEP). Early biobehavioral prevention and treatment interventions are needed for TG youth.
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