Development of beta-type Ti-Nb-Zr-Mo alloys for orthopedic applications
Development of beta-type Ti-Nb-Zr-Mo alloys for orthopedic applications
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DOI：
10.1016/j.apmt.2021.100968
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发表时间：
2021-02-11
影响因子：
8.3
通讯作者：
Wen, Cuie
中科院分区：
文献类型：
--
作者：
Weng, Weijie;Biesiekierski, Arne;Wen, Cuie
本研究研究了新设计的用于骨科的β (β)型Ti-Nb-Zr-Mo （TNZM）合金的显微组织、力学性能和细胞相容性。TNZM合金的制备方法为冷坩埚悬浮熔炼，其标称成分（wt.%）分别为Ti-24Nb-38Zr-2Mo （TNZM1）、Ti-27Nb-33Zr-2Mo （TNZM2）、Ti-30Nb-28Zr-2Mo （TNZM3）和Ti-37Nb-16Zr-2Mo （TNZM4）。显微组织研究表明，4种TNZM合金的初生相均为体心立方组织（13型），具有相同的粗晶和致密的亚晶界。维氏硬度依次为TNZM2 (244 +/- 8 HV) > TNZM1 (239 +/- 6 HV) > TNZM3 (235 +/- 6 HV) > TNZM4 (220 +/- 6 HV)；随着应变的增大，TNZM4合金的流变应力略低于其他三种合金，但TNZM合金的抗压屈服强度差异不显著。在592 ~ 702 MPa（抗拉强度）、584 ~ 695 MPa（抗拉屈服强度）、10 ~ 16%（失效伸长率）和68 ~ 73 GPa（杨氏模量）范围内测定了TNZM合金的拉伸性能。细胞相容性试验表明，所有TNZM合金均具有良好的细胞相容性。因此，TNZM1、TNZM2和TNZM3具有比4级纯钛和Ti-6Al-4V合金更高的弹性允许应变（0.95-0.99%）、高维氏硬度、超高延展性和良好的细胞相容性，被推荐为骨科应用的有前景的候选材料。(C) 2021 Elsevier Ltd版权所有。
This study investigated the microstructure, mechanical properties, and cytocompatibility of the newly designed beta (beta)-type Ti-Nb-Zr-Mo (TNZM) alloys for orthopedic applications. The fabrication method of TNZM alloys was cold-crucible levitation melting, their nominal compositions (wt.%) were Ti-24Nb-38Zr-2Mo (TNZM1), Ti-27Nb-33Zr-2Mo (TNZM2), Ti-30Nb-28Zr-2Mo (TNZM3) and Ti-37Nb-16Zr-2Mo (TNZM4). Microstructural investigation revealed four TNZM alloys consisted of body-centered-cubic structure (13type) as their primary phase, with identical coarse grains and dense sub-grain boundaries. The Vickers hardness descended as TNZM2 (244 +/- 8 HV) > TNZM1 (239 +/- 6 HV) > TNZM3 (235 +/- 6 HV) > TNZM4 (220 +/- 6 HV); no significant difference was found among the compressive yield strengths of TNZM alloys, although TNZM4 showed a slightly lower flow stress than those of the other three alloys as the strain increases. Tensile properties of TNZM alloys were measured in the ranges of 592-702 MPa (tensile strength), 584-695 MPa (tensile yield strength), 10-16% (elongation to failure) and 68-73 GPa (Young's modulus). Cytocompatibility tests indicated that all TNZM alloys possessed good cytocompatibility. Thus, TNZM1, TNZM2 and TNZM3 were recommended as promising candidates for orthopedic applications as they possess higher elastic admissible strain (0.95-0.99%) than those of Grade-4 commercially pure titanium and mill-annealed Ti-6Al-4V alloy, high Vickers hardness, ultrahigh malleability, and good cytocompatibility. (C) 2021 Elsevier Ltd. All rights reserved.