CluSTr: a database of clusters of SWISS-PROT plus TrEMBL proteins
CluSTr: a database of clusters of SWISS-PROT plus TrEMBL proteins
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DOI：
10.1093/nar/29.1.33
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发表时间：
2001-01-01
影响因子：
14.9
通讯作者：
Apweiler, R
中科院分区：
文献类型：
--
作者：
Kriventseva, EV;Fleischmann, W;Apweiler, R
CluSTr （Clusters of SWISS-PROT and TrEMBL蛋白）数据库提供了SWISS-PROT和TrEMBL蛋白的自动分类。聚类是基于对蛋白质序列之间所有两两比较的分析。对不同水平的蛋白质相似性进行了分析，得出了集群的分层组织。该数据库提供到InterPro的链接，InterPro集成了PROSITE、PRINTS、Pfam和ProDom中蛋白质家族、结构域和功能位点的信息。到InterPro图形界面的链接允许用户一眼看到来自集群的蛋白质是否共享特定的功能位点。CluSTr还提供对HSSP和PDB的交叉引用。该数据库可在http://www.ebi.ac.uk/clustr上查询和浏览。
The CluSTr (Clusters of SWISS-PROT and TrEMBL proteins) database offers an automatic classification of SWISS-PROT and TrEMBL proteins into groups of related proteins. The clustering is based on analysis of all pairwise comparisons between protein sequences. Analysis has been carried out for different levels of protein similarity, yielding a hierarchical organisation of clusters. The database provides links to InterPro, which integrates information on protein families, domains and functional sites from PROSITE, PRINTS, Pfam and ProDom. Links to the InterPro graphical interface allow users to see at a glance whether proteins from the cluster share particular functional sites. CluSTr also provides cross-references to HSSP and PDB. The database is available for querying and browsing at http://www.ebi.ac.uk/clustr.