Multifactorial inheritance with cultural transmission and assortative mating. II. a general model of combined polygenic and cultural inheritance.
Multifactorial inheritance with cultural transmission and assortative mating. II. a general model of combined polygenic and cultural inheritance.
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DOI：
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发表时间：
1979-03
影响因子：
9.8
通讯作者：
C. Robert Cloninger;J. Rice;T. Reich
中科院分区：
文献类型：
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作者：
C. Robert Cloninger;J. Rice;T. Reich
一个一般的线性模型相结合的多基因文化遗传。该模型考虑了表型选择性交配、共同环境、母本和父本效应以及基因-文化相关性。本文给出了一次交配和二次交配的家系成员表型相关的一般公式。一个FORTRAN程序测试版，可根据要求，用于提供最大似然估计的参数从报告的相关性。分析了美国的智商和伯克斯文化指数的数据。文化和遗传成分的表型方差的观察，使显着和实质性的贡献，在智商的家族相似性。DZ双胞胎的环境之间的相关性被发现等于单胞胎兄弟姐妹，而不是MZ双胞胎。伯克斯的文化指数被发现是一个不完美的测量中父母的智商，而不是一个指数的家庭环境，因为以前的假设。在此条件下，该模型的参数可以是唯一的和精确的估计进行了讨论。解释方差分量的存在下，重复交配和基因文化的协方差进行审查。一个保守的，但强大的，环境指数的使用方法进行说明。
A general linear model of combined polygenic-cultural inheritance is described. The model allows for phenotypic assortative mating, common environment, maternal and paternal effects, and genic-cultural correlation. General formulae for phenotypic correlation between family members in extended pedigrees are given for both primary and secondary assortative mating. A FORTRAN program BETA, available upon request, is used to provide maximum likelihood estimates of the parameters from reported correlations. American data about IQ and Burks' culture index are analyzed. Both cultural and genetic components of phenotypic variance are observed to make significant and substantial contributions to familial resemblance in IQ. The correlation between the environments of DZ twins is found to equal that of singleton sibs, not that of MZ twins. Burks' culture index is found to be an imperfect measure of midparent IQ rather than an index of home environment as previously assumed. Conditions under which the parameters of the model may be uniquely and precisely estimated are discussed. Interpretation of variance components in the presence of assortative mating and genic-cultural covariance is reviewed. A conservative, but robust, approach to the use of environmental indices is described.