Heteronuclear NMR studies of cobalamins. 2. Carbon-13 and phosphorus-31 NMR studies of [13C]cyanocobalamin
Heteronuclear NMR studies of cobalamins. 2. Carbon-13 and phosphorus-31 NMR studies of [13C]cyanocobalamin
复制标题
钴胺素的异核核磁共振研究。
DOI：
10.1021/ic00180a022
复制
发表时间：
1984
影响因子：
4.6
通讯作者：
J. Hakimi
中科院分区：
文献类型：
--
作者：
K. Brown;J. Hakimi
结论由于磺酰胺键的稳定性，如果试剂含有合适的位点，最好是胺基，则各种试剂都可以掺入到p-氯磺化聚苯乙烯膜中。此外，聚苯乙烯薄膜可以通过蒸发浇铸到几乎任何表面上。因此，这里描述的结果是值得注意的，因为它们提供了一个广泛的基础上，一般的方法来控制纳入氧化还原位点和氧化还原位点的组合到theelectro-trode-film界面。如电化学、光谱和激发态测量所示，结合的氧化还原位点保留了它们的溶液类似物的许多性质。由于它们的性质，这些膜已被用于许多应用中，其中一些在方案I中以概括的形式示出，并且包括以下：（1）两个氧化还原对和潜在的激发态/猝灭剂对[（bpy）2 Ru（5-phenNH-）2+]/[（CH 3）2-（NC 6 H 4 NH-）]的共结合，（2）阳离子络合物的水解和随后通过离子交换的结合，（3）含有相对强发射激发态的膜的制备，和（4）氧化还原双层的制备。感谢陆军研究中心（Army Research Center）对本研究的支持，批准号为DAAG 29 - 790 C-0044。作者感谢乔治塞缪尔博士对聚苯乙烯样品的初步工作，以及鲁思·弗赖塔格、拉斯·施梅尔博士和达里尔·H教授赠送的化学品。布施
ConclusionsThe results described here show that a variety of reagents can be incorporated into/>-chlorosulfonated polystyrene films if the reagnet contains an appropriate site, preferably an amine group, because of the stability of the resulting sulfonamide link. In addition, the polystyrene films can be cast onto virtually any surface by evaporation. As a consequence, the results described here are notable since they offer a broadly based, general approach to the controlled incorporation of redox sites and combinations of redox sites into theelec-trode-film interface. As shown by electrochemical, spectral, and excited-state measurements, the bound redox sites retain many of the properties of their solution analogues. Because of their properties, the films have found use in a number of applications, some of which are shown in summary form in Scheme I and which include the following:(1) the co-incorporation of two redox couples and of a potential excited state/quencher pair,[(bpy) 2Ru (5-phenNH-) 2+]/[(CH3) 2-(NC6H4NH-)],(2) hydrolysis andsubsequent binding of cationic complexes by ion exchange,(3) the preparation of films containing relatively strongly emitting excited states, and (4) the preparation of redox bilayers. Acknowledgments are made to the Army Research Office—Durham under Grant No. DAAG29-790C-0044 for support of this research. The authors gratefully acknowledge the initial work on the polystyrene samples by Dr. George Samuels and the gift of chemicals from Ruth Freitag, Dr. Russ Schmehl, and Professor Daryle H. Busch.