Digoxin as an emerging therapy in noncardiac diseases.

Digoxin as an emerging therapy in noncardiac diseases.
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DOI:
10.1016/j.tips.2022.10.002
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发表时间:
2022-11
影响因子:
13.8
通讯作者:
F. Dashti;Fatima Jamshed;Xinshou Ouyang;W. Mehal;B. Banini
F. Dashti;Fatima Jamshed;Xinshou Ouyang;W. Mehal;B. Banini
中科院分区:
医学1区
文献类型:
--
作者:
F. Dashti;Fatima Jamshed;Xinshou Ouyang;W. Mehal;B. Banini

文献摘要

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心苷(CG)地高辛是一种被批准用于治疗心力衰竭和室上性心律失常的仿制药。在过去的几十年里,在重新调整地高辛的用途以治疗各种非心脏病方面取得了实质性的进展。在这里,我们评估与非心脏使用地高辛相关的基础和临床工作的最新见解。
The cardiac glycoside (CG) digoxin is a generic drug approved for the treatment of heart failure and supraventricular arrhythmias. Over the past few decades, substantial strides have been made toward repurposing digoxin to treat various noncardiac diseases. Here, we evaluate recent insights into basic and clinical work related to noncardiac use of digoxin.