Cysteamine: a potent and specific depletor of pituitary prolactin.
Cysteamine: a potent and specific depletor of pituitary prolactin.
复制标题
半胱胺：垂体催乳素的有效且特异性消耗剂。
DOI：
10.1126/science.7089575
复制
发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Martin,JB
中科院分区：
文献类型：
--
作者：
Millard,WJ;Sagar,SM;Landis,DM;Martin,JB
半胱胺能在体内和体外迅速降低垂体组织中催乳素的浓度。效果是剂量依赖性的，可逆的，不能用催乳素释放来解释。通过电子显微镜观察，半胱胺似乎不会通过多巴胺受体发挥作用，也不会改变乳质体的形态。
Cysteamine rapidly reduces the concentration of prolactin in pituitary tissue in vivo and in vitro. The effect is dose-dependent, reversible, and cannot be accounted for by prolactin release. Cysteamine does not appear to exert its effect through dopamine receptors and does not alter lactotrope morphology, as determined by electron microscopy.