Marmoset models commonly used in biomedical research.
Marmoset models commonly used in biomedical research.
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作者：
K. Mansfield
普通狨猴（Callithrix jacchus）是一种小型、非濒危的新大陆灵长类动物，原产于巴西，已广泛用于生物医学研究。在历史上，普通的绒猴被用于神经科学、生殖生物学、传染病和行为研究。近年来，该物种已越来越多地用于药物开发和安全性评估。优点涉及尺寸、成本、饲养和生物安全问题以及可用于模型开发的独特生理差异。圈养繁殖的可用性和容易性表明，它们可能是更传统的非人类灵长类动物的替代物种。在生物医学研究中常用的绒猴模型，重点是那些可能提供一种替代传统的非人灵长类动物物种。
The common marmoset (Callithrix jacchus) is a small, nonendangered New World primate that is native to Brazil and has been used extensively in biomedical research. Historically the common marmoset has been used in neuroscience, reproductive biology, infectious disease, and behavioral research. Recently, the species has been used increasingly in drug development and safety assessment. Advantages relate to size, cost, husbandry, and biosafety issues as well as unique physiologic differences that may be used in model development. Availability and ease of breeding in captivity suggest that they may represent an alternative species to more traditional nonhuman primates. The marmoset models commonly used in biomedical research are presented, with emphasis on those that may provide an alternative to traditional nonhuman primate species.