Confocal microlaparoscope for imaging the fallopian tube.
Confocal microlaparoscope for imaging the fallopian tube.
复制标题
用于输卵管成像的共焦显微腹腔镜。
DOI：
10.1117/1.jbo.19.11.116010
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发表时间：
2014
影响因子：
3.5
通讯作者：
Gmitro,ArthurF
中科院分区：
文献类型：
--
作者：
Wu,Tzu-Yu;Rouse,AndrewR;Chambers,SetsukoK;Hatch,KennethD;Gmitro,ArthurF
最近的证据表明，卵巢癌可以起源于输卵管。与许多其他癌症不同的是，卵巢和输卵管难以进入限制了研究这种致命疾病进展的能力，并在最适合治疗的早期阶段对其进行诊断。一个刚性共焦显微腹腔镜系统设计的图像上皮表面的卵巢在体内以前的报告。一种新型的具有铰接远端的共焦显微腹腔镜已经被开发出来，以实现活体进入人类输卵管。新型微型腹腔镜与5 mm套管针兼容，包括一个直径为2.2 mm的铰接远端头端，由一个裸光纤束和一个用于荧光共聚焦成像的自动染料输送系统组成。这个小关节装置应使共焦显微腹腔镜图像早期卵巢癌内出现的输卵管exvivoimages的动物组织和人类输卵管使用新的关节装置提出沿着内vivoimaging结果使用刚性共焦显微腹腔镜系统。
Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. A rigid confocal microlaparoscope system designed to image the epithelial surface of the ovaryin vivowas previously reported. A new confocal microlaparoscope with an articulating distal tip has been developed to enablein vivoaccess to human fallopian tubes. The new microlaparoscope is compatible with 5-mm trocars and includes a 2.2-mm-diameter articulating distal tip consisting of a bare fiber bundle and an automated dye delivery system for fluorescence confocal imaging. This small articulating device should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube.Ex vivoimages of animal tissue and human fallopian tube using the new articulating device are presented along within vivoimaging results using the rigid confocal microlaparoscope system.