Scalene muscle activity during progressive inspiratory loading under pressure support ventilation in normal humans
Scalene muscle activity during progressive inspiratory loading under pressure support ventilation in normal humans
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DOI：
10.1016/j.resp.2008.09.010
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发表时间：
2008-12-31
影响因子：
2.3
通讯作者：
Hug, Francois
中科院分区：
文献类型：
--
作者：
Chiti, Linda;Biondi, Giuseppina;Hug, Francois
我们假设：(1)在接受间歇性正压无创通气的健康人中，呼吸机触发敏感度的变化将与鳞片烯活动增加相关，(2)如果通过吸气锁相平均表面肌电(EMG)适当处理，鳞片烯将可靠地检测到并量化这一点，(3)呼吸困难和鳞片烯EMG之间将存在相关性。对10例受试者斜角肌表面和肌内肌电活动进行了测量。他们通过面罩静静呼吸10分钟，然后连接到机械呼吸机。记录是在三个15分钟的时间段内进行的，受试者在不断增加的负压触发下呼吸(最大吸气压的-5%、-10%和-15%)。随着吸气触发值的增加，吸气努力、呼吸困难和角叉烯活动显著增加。鳞片状肌电活动水平与食道压力时间乘积和呼吸困难程度相关。经吸气调整的表面肌电信号平均值可用于检测机械通气过程中斜角肌活动的轻微增加。(C)2008爱思唯尔B.V.保留所有权利。
We hypothesized that(I)in healthy humans subjected to intermittent positive pressure non-invasive ventilation, changes in the ventilator trigger sensitivity Would be associated with increased scalene activity, (2) if properly processed - through inspiratory phase-locked averaging - surface electromyograms (EMG) of the scalenes would reliably detect and quantify this, (3) there would be a correlation between dyspnea and scalene EMG. Surface and intramuscular EMG activity of scalene muscles were measured in 10 subjects. They breathed quietly through a face mask for 10 min and then were connected to a mechanical ventilator. Recordings were performed during three 15-min epochs where the Subjects breathed against an increasingly negative pressure trigger (-5%, -10% and -15% of maximal inspiratory pressure). With increasing values of the inspiratory trigger, inspiratory efforts, dyspnea and the scalene activity increased significantly. The scalene EMG activity level was correlated with the esophageal pressure time product and with dyspnea intensity. Inspiration-adjusted Surface EMG averaging could be useful to detect small increases of the scalene muscles activity during mechanical ventilation. (C) 2008 Elsevier B.V. All rights reserved.