EVIDENCE OF REDISTRIBUTION OF CARDIAC-OUTPUT IN ASYMMETRICAL GROWTH-RETARDATION
EVIDENCE OF REDISTRIBUTION OF CARDIAC-OUTPUT IN ASYMMETRICAL GROWTH-RETARDATION
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DOI：
10.1111/j.1471-0528.1989.tb03285.x
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发表时间：
1989-06-01
期刊：
影响因子：
--
通讯作者：
ALLAN, LD
中科院分区：
文献类型：
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作者：
ALGHAZALI, W;CHITA, SK;ALLAN, LD
本文应用多普勒超声技术测定了31例生长迟缓胎儿心脏两侧心输出量。头腹围比大于第95百分位数的16个胎儿被诊断为不对称性生长迟缓。15例对称性生长迟缓胎儿心输出量分布正常。肺动脉和主动脉的平均血流速度和最大血流速度与正常胎儿相似，右心的计算输出量大于左心。右心血流量占合并心输出量的百分比与正常胎儿相比无统计学显著性差异。与此相反，所有16个胎儿不对称生长迟缓有较高的平均和最大速度在主动脉比肺动脉。计算出的每侧心脏的体积流量显示，15例患者的左心输出量大于右心输出量。右心血流量占合并心输出量的百分比与正常胎儿的值有统计学差异。这些发现与胎儿血流再分配的理论一致，即脑血流优先“备用”。
Thirty-one fetuses with growth retardation were studied by Doppler estimation of the cardiac output from each side of the fetal heart. Asymmetrical growth retardation was diagnosed in 16 fetuses by a head to abdominal circumference ratio above the 95th centile. In the 15 fetuses with symmetrical growth retardation, the distribution of cardiac output was normal. The mean and maximum velocity of blood flow in the pulmonary artery and aorta were similar to values in normal fetuses, and there was a greater calculated output from the right heart than from the left. The right heart flow expressed as a percentage of the combined cardiac output was not statistically significantly different from that in normal fetuses. In contrast, all 16 fetuses with asymmetrical growth retardation had a higher mean and maximum velocity in the aorta than in the pulmonary artery. The calculated volume flow from each side of the heart showed a greater output from the left than the right heart in 15. The right heart flow expressed as a percentage of the combined cardiac output was statistically different from the value in noral fetuses. These findings are consistent with theories of the redistribution of fetal blood flow, where cerebral blood flow is preferentially ''spared''.