ELICITATION OF REFLEX VAGAL RELAXATION OF STOMACH FROM PHARYNX AND ESOPHAGUS IN CAT
ELICITATION OF REFLEX VAGAL RELAXATION OF STOMACH FROM PHARYNX AND ESOPHAGUS IN CAT
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DOI：
10.1111/j.1748-1716.1969.tb04561.x
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发表时间：
1969-01-01
期刊：
影响因子：
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通讯作者：
JANSSON, G
中科院分区：
文献类型：
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作者：
ABRAHAMSSON, H;JANSSON, G
氯化猫食道的不同部分扩张导致迅速和显著的胃部松弛。即使是轻微的扩张也足以引起胃松弛，松弛程度随着食道扩张而消失。胃舒张性反应是由于迷走-迷走神经反射引起的。这种反应也可以在切断脊髓连接后引起，但在迷走神经切断术后消失。它不能被阿托品或金刚乙胺所阻断。因此，它类似于通过直接电刺激迷走神经“松弛”纤维到胃而获得的胃松弛。结果表明，这些纤维构成了所观察到的食道-胃迷走神经-迷走神经松弛反射的传出通路。此外，在咽部引起吞咽时，也记录到类似的胃松弛，由迷走神经传出的松弛纤维介导。据推测，在吞咽过程中，所描述的胃松弛模式在胃的“接受性松弛”中起重要作用。
Distension of different parts of the esophagus in chloralosed cats caused prompt and pronounced relaxation of the stomach. Even slight distension was sufficient to elicit gastric relaxation, and the degree of relaxation vaned with that of the esophageal distension. The gastric relaxatory response was shown to be due to elicitation of a vago‐vagal reflex to the stomach. The response could be elicited also after exclusion of spinal connections, but disappeared after vagotomy. It couldnotbe blocked by atropine or guanethidine. It thus resembled the gastric relaxation obtained by direct electric stimulation of the vagal “relaxatory” fibres to the stomach. It is concluded that these fibres constitute the efferent pathway of the observed esophageo‐gastric vago‐vagal relaxatory reflex.—Furthermore, a similar gastric relaxation, mediatedviathe vagal efferent relaxatory fibres, was recorded in connection with pharyngeally elicited swallowing. It is assumed that the gastric relaxation pattern described plays an essential role in “receptive relaxation” of the stomach during deglutition.