MR imaging in patients at risk for developing nephrogenic systemic fibrosis: protocols, practices, and imaging techniques to maximize patient safety.
MR imaging in patients at risk for developing nephrogenic systemic fibrosis: protocols, practices, and imaging techniques to maximize patient safety.
复制标题
对有肾源性系统性纤维化风险的患者进行 MR 成像：方案、实践和成像技术，以最大限度地提高患者安全。
DOI：
10.1148/rg.291085072
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Bluemke,DavidA
中科院分区：
文献类型：
--
作者：
Juluru,Krishna;Vogel-Claussen,Jens;Macura,KatarzynaJ;Kamel,IhabR;Steever,Alexander;Bluemke,DavidA
Nephrogenic systemic fibrosis (NSF) is a rare but potentially debilitating or even fatal fibrosing condition that most often affects the skin but is now also recognized to involve multiple organs. The first report on NSF was published in 1997, and there is mounting evidence that this condition is associated with renal failure and the administration of large amounts of gadolinium. Although gadolinium-enhanced magnetic resonance (MR) imaging was once considered one of the safer imaging procedures, concerns over NSF have led the radiology community to rethink its imaging practices. Several noncontrast angiographic techniques based on fast spin-echo, gradient-echo, phase-contrast, and inversion-recovery principles are currently available. These techniques allow MR angiography to be performed safely, even in patients at risk for developing NSF. When use of gadolinium-based contrast material is necessary for diagnosis, it is possible to reduce total gadolinium administration through the use of agents with higher relaxivity, time-resolved imaging, high-field-strength magnets, and body compression devices. Management of NSF also requires an understanding of the risk factors of this disease and developing an institutional policy for identifying and testing at-risk patients.© RSNA, 2008
