Information perspectives of the Haseman-Elston method.
Information perspectives of the Haseman-Elston method.
复制标题
Haseman-Elston 方法的信息视角。
DOI：
10.1159/000072318
复制
发表时间：
2003
期刊：
影响因子：
1.8
通讯作者：
Wright,FredA
中科院分区：
文献类型：
--
作者：
Wright,FredA
The Haseman-Elston regression approach can be viewed as a special case in a larger framework in which independent sibling pairs are ascertained, perhaps based on their phenotypes. Using likelihood arguments in an idealized setting, expressions are obtained for the inherent linkage information contained in the phenotype distributions. The results provide insight and analytic results that apply to general phenotype distributions and can be used to judge the effects of various data transformations and selective sampling of extreme phenotypes.
