Effect of sleep on epilepsy
Effect of sleep on epilepsy
复制标题
DOI：
10.1097/00004691-200212000-00003
复制
发表时间：
2002-12-01
影响因子：
2.4
通讯作者：
Dinner, DS
中科院分区：
文献类型：
--
作者：
Dinner, DS
睡眠与癫痫之间有着极其密切的关系。在这篇手稿中，我将回顾睡眠对癫痫的影响。睡眠是发作间期癫痫样放电的有效激活剂。儿童良性局灶性癫痫在清醒时很少出现尖波，但在睡眠时每页可能会出现几次放电。在慢波睡眠期间伴有癫痫电持续状态的脑病综合征中，在非快速眼动睡眠中，发作间期放电几乎是连续的。在一些韦斯特综合征患者中，高节律失常模式可能只出现在睡眠中，而在其他患者中，放电可能以半周期性方式增加，导致爆发抑制样模式。在某些癫痫综合征中，癫痫发作似乎与睡眠有非常密切的关系。在儿童良性局灶性癫痫中，癫痫发作几乎完全发生在睡眠中，而补充性感觉运动区癫痫发作往往在睡眠期间成群发生。青少年肌阵挛性癫痫与睡眠-觉醒周期有密切关系，癫痫发作往往主要发生在觉醒时。我还讨论了睡眠和睡眠剥夺在癫痫脑电图评估中的作用。
There is an extremely intimate relationship between sleep and epilepsy. In this manuscript I will review the influence that sleep has on epilepsy. Sleep is a potent activator of interictal epileptiform discharges. Sharp waves are infrequent during wakefulness in benign focal epilepsy of childhood, but may occur in runs of several discharges per page in sleep. The interictal discharges become almost continuous in non-REM sleep in the syndrome of encephalopathy with electrical status epilepticus during slow wave sleep. In some patients with West syndrome a hypsarrhythmia pattern may only appear in sleep whereas in others there may be an increase in discharges in a semiperiodic fashion resulting in a burst-suppression like pattern. Seizures appear to have a very close relationship with sleep in certain epilepsy syndromes. In benign focal epilepsy of childhood the seizures occur almost exclusively in sleep, while supplementary sensorimototor area seizures tend to occur in clusters during sleep. Juvenile myoclonic epilepsy has a close relationship with the sleep-wake cycle with seizures tending to occur predominantly on awakening. I also discuss the role of sleep and sleep deprivation in the EEG evaluation of epilepsy.