VFDB: a reference database for bacterial virulence factors.
VFDB: a reference database for bacterial virulence factors.
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DOI：
10.1093/nar/gki008
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Jin Q
中科院分区：
文献类型：
--
作者：
Chen L;Yang J;Yu J;Yao Z;Sun L;Shen Y;Jin Q
在21世纪世纪，细菌病原体继续对全世界的公共健康构成重大威胁。在过去的几十年里，对细菌致病机理的深入研究极大地扩展了我们对疾病过程分子水平机制的认识。为了促进未来的研究，有必要形成一个数据库，共同呈现各种医学上重要的细菌病原体的毒力因子（VF）。毒力因子数据库（VFDB）（http：//www.mgc.ac.cn/VFs/）的目的是为科学家提供一个快速获取各种细菌病原体毒力因子最新知识的资源。VFDB是全面和用户友好的。人们可以通过浏览每个属或键入关键字来搜索VFDB。此外，还可以使用针对所有已知VF相关基因的BLAST搜索工具。VFDB提供了一个统一的网关来存储，搜索，检索和更新有关各种细菌病原体的VF的信息。
Bacterial pathogens continue to impose a major threat to public health worldwide in the 21st century. Intensified studies on bacterial pathogenesis have greatly expanded our knowledge about the mechanisms of the disease processes at the molecular level over the last decades. To facilitate future research, it becomes necessary to form a database collectively presenting the virulence factors (VFs) of various medical significant bacterial pathogens. The aim of virulence factor database (VFDB) (http://www.mgc.ac.cn/VFs/) is to provide such a source for scientists to rapidly access to current knowledge about VFs from various bacterial pathogens. VFDB is comprehensive and user-friendly. One can search VFDB by browsing each genus or by typing keywords. Furthermore, a BLAST search tool against all known VF-related genes is also available. VFDB provides a unified gateway to store, search, retrieve and update information about VFs from various bacterial pathogens.