Binaural Interaction Effects of 30-50 Hz Auditory Steady State Responses
Binaural Interaction Effects of 30-50 Hz Auditory Steady State Responses
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DOI：
10.1097/aud.0000000000000429
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发表时间：
2017-09-01
期刊：
影响因子：
3.7
通讯作者：
Wouters, Jan
中科院分区：
文献类型：
--
作者：
Gransier, Robin;van Wieringen, Astrid;Wouters, Jan
目的：通过 30 至 50 Hz 区域内的调制频率调制的听觉刺激可引起成人高信噪比的听觉稳态反应 (ASSR)，并可用于确定无法可靠给出行为反馈的成人的特定频率听力阈值。为了尽可能有效地测量 ASSR，可以使用多重刺激范例，同时刺激双耳。然而，当双耳同时受到刺激时，30 至 50Hz ASSR 的响应强度会受到影响。本研究的目的是通过系统地研究正常听力成人中 30 至 50 Hz ASSR 的双耳交互效应，深入了解 2 耳刺激范式引发的 30 至 50 Hz ASSR 的测量效率。 设计：使用 64 通道 EEG 系统在 23 名正常听力成年人中获得 ASSR。所有参与者都参与了一种双耳障碍、多种双耳障碍和多种单耳障碍。刺激由调制的 1 倍频程噪声带组成，中心频率为 1 kHz，声压级为 70 dB。昏迷状态包含向双耳提供 40 Hz 调制刺激。在双耳条件下，左耳刺激的调制频率保持恒定在 40 Hz，而右耳刺激要么是未调制的，要么是调制的载波。对于调制载波，调制频率在不同条件下以 2 Hz 为步长在 30 至 50 Hz 之间变化。单耳条件包括双耳和双耳条件中包含的所有刺激。结果：调制频率 >= 36 Hz 导致所有参与者在单耳条件下出现显着的 ASSR。在双耳条件下观察到显着的增强效果（平均：类似于3dB），而在双耳条件下观察到显着的降低效果。刺激的时间特征对减少量没有明显影响。对于调制频率 >= 40 Hz 诱发的 ASSR，衰减率为 33% >3 dB；对于调制频率 = 40 Hz 诱发的 ASSR，衰减率为 50%），在 66% 的病例中，比 1 耳顺序刺激范例更有效。
Objectives: Auditory stimuli modulated by modulation frequencies within the 30 to 50 Hz region evoke auditory steady state responses (ASSRs) with high signal to noise ratios in adults, and can be used to determine the frequency-specific hearing thresholds of adults who are unable to give behavioral feedback reliably. To measure ASSRs as efficiently as possible a multiple stimulus paradigm can be used, stimulating both ears simultaneously. The response strength of 30 to 50Hz ASSRs is, however, affected when both ears are stimulated simultaneously. The aim of the present study is to gain insight in the measurement efficiency of 30 to 50 Hz ASSRs evoked with a 2-ear stimulation paradigm, by systematically investigating the binaural interaction effects of 30 to 50 Hz ASSRs in normal-hearing adults.Design: ASSRs were obtained with a 64-channel EEG system in 23 normal-hearing adults. All participants participated in one diotic, multiple dichotic, and multiple monaural conditions. Stimuli consisted of a modulated one-octave noise band, centered at 1 kHz, and presented at 70 dB SPL. The diotic condition contained 40 Hz modulated stimuli presented to both ears. In the dichotic conditions, the modulation frequency of the left ear stimulus was kept constant at 40 Hz, while the stimulus at the right ear was either the unmodulated or modulated carrier. In case of the modulated carrier, the modulation frequency varied between 30 and 50 Hz in steps of 2 Hz across conditions. The monaural conditions consisted of all stimuli included in the diotic and dichotic conditions.Results: Modulation frequencies >= 36 Hz resulted in prominent ASSRs in all participants for the monaural conditions. A significant enhancement effect was observed (average: similar to 3 dB) in the diotic condition, whereas a significant reduction effect was observed in the dichotic conditions. There was no distinct effect of the temporal characteristics of the stimuli on the amount of reduction. The attenuation was in 33% of the cases >3 dB for ASSRs evoked with modulation frequencies >= 40 Hz and 50% for ASSRs evoked with modulation frequencies = 40 Hz), more efficient than a 1-ear sequential stimulation paradigm in 66% of the cases.