Uneventful administration of plasma products in a recipient with T-activated red cells.
Uneventful administration of plasma products in a recipient with T-activated red cells.
复制标题
对具有 T 激活红细胞的受体进行血浆产品的顺利施用。
DOI：
10.1046/j.1537-2995.1986.26286152912.x
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发表时间：
1986
期刊：
影响因子：
2.9
通讯作者：
Simon,T
中科院分区：
文献类型：
--
作者：
Eversole,M;Nonemaker,B;Zurek,K;South,S;Simon,T
一个患有T -多凝集性红细胞和严重凝血功能障碍的患者提供了一个观察血浆输注面对T -激活的结果的机会。患者是一名52岁的纳瓦霍印第安人，胆囊穿孔并由产气荚膜梭菌引起的败血症。手术切除了胆囊。术后，他有严重的血小板减少，部分凝血活素和凝血酶原时间延长。患者红细胞被花生和甘氨酸凝集素凝集，但被鼠尾草、鼠尾草和扁豆提取物凝集不。当患者给予血小板浓缩物和4单位单一供体血浆时，未观察到不良反应或任何溶血迹象。血浆血红蛋白和触珠蛋白水平显示无溶血。他的凝血功能有了反应，他成功地进行了手术探查和恢复。本病例证明，T活化红细胞受体输血并不一定会产生严重的不良后果。T激活是血浆输注的相对禁忌症，但不是绝对禁忌症。
A patient with T‐polyagglutinable red cells and a severe coagulopathy provided an opportunity to observe the results of plasma transfusion in the face of T‐activation. The patient was a 52‐year‐old Navajo Indian with a perforated gall bladder and related sepsis due toClostridium perfringens.The gall bladder was removed surgically. Postoperatively, he had severe thrombocytopenia, and prolonged partial thromboplastin and prothrombin times. The patient's red cells were agglutinated byArachis hypogaeaandGlycine sojalectins but were unagglutinated by extracts ofSalvia horminum, Salvia sclarea, andBandeiraea simplicifolia.No untoward reactions or any evidence of hemolysis were observed when the patient was given platelet concentrates and 4 units of single‐donor plasma. Serial plasma hemoglobin and haptoglobin levels documented that there was no hemolysis. His coagulopathy responded, and he had a successful surgical re‐exploration and recovery. This case documents that serious adverse consequences do not necessarily follow transfusion of plasma in a recipient with T‐activated red cells. T‐activation is a relative but not absolute contraindication to plasma transfusion.