PERFEX - AN EXPERT-SYSTEM FOR INTERPRETING 3D MYOCARDIAL PERFUSION
PERFEX - AN EXPERT-SYSTEM FOR INTERPRETING 3D MYOCARDIAL PERFUSION
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DOI：
10.1016/0957-4174(93)90038-8
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发表时间：
1993-10-01
影响因子：
8.5
通讯作者：
GARCIA, EV
中科院分区：
文献类型：
--
作者：
EZQUERRA, N;MULLICK, R;GARCIA, EV
解释三维（3D）数据通常被认为是一个不明确的和信息密集型的任务。在医学诊断图像的背景下，任务变得越来越困难，其中视觉信息必须结合其他非视觉信息来解释。提出了一种新的方法来执行这样的多维信息的解释，集中在医学上的重要应用：心肌灌注分布的三维断层图像的解释。总体目标是协助冠状动脉疾病的诊断。该方法采用基于知识的方法来处理和映射的3D视觉信息到符号表示，随后用于推断结构（解剖）从功能（生理），以及解释灌注再分布的时间效应，并评估心血管疾病的程度和严重程度的定量和定性。基于知识的系统在交互式框架中以视觉和文本形式呈现所得到的诊断建议，从而提高整体效用。本文介绍了这种方法的基础，包括在实际的临床环境中，该系统的实施和测试的方法。
Interpreting three-dimensional (3D) data is generally recognized as an ill-defined and information-intensive task. The task becomes increasingly difficult in the context of medical diagnostic imagery, wherein the visual information must be interpreted in conjunction with other, nonvisual information. A novel approach is presented to perform the interpretation of such multidimensional information, concentrating on a medically important application: the interpretation of 3D tomograms of myocardial perfusion distribution. The overall goal is to assist in the diagnosis of coronary artery disease. The approach employs knowledge-based methods to process and map the 3D visual information into symbolic representations, which are subsequently used to infer structure (anatomy) from function (physiology), as well as to interpret the temporal effects of perfusion redistribution, and assess the extent and severity of cardiovascular disease both quantitatively and qualitatively. The knowledge-based system presents the resulting diagnostic recommendations in both visual and textual forms in an interactive framework, thereby enhancing overall utility. This paper presents the methodology underlying this approach, including the implementation and testing of this system within an actual clinical environment.